| Identification | More | [Name]
3-(Difluoromethoxy)aniline | [CAS]
22236-08-4 | [Synonyms]
3-AMINO-ALPHA,ALPHA-DIFLUOROANISOLE
3-(DIFLUOROMETHOXY)ANILINE
ALPHA,ALPHA-DIFLUORO-M-ANISIDINE
BUTTPARK 45\03-43
3-(Difluoromethoxy)aniline 98%
3-(Difluoromethoxy)aniline98%
3-Difluoromethoxy-phenylamine | [Molecular Formula]
C7H7F2NO | [MDL Number]
MFCD00236221 | [Molecular Weight]
159.13 | [MOL File]
22236-08-4.mol |
| Chemical Properties | Back Directory | [Boiling point ]
201-202 °C (lit.) | [density ]
1.276 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.5100(lit.)
| [Fp ]
225 °F
| [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [form ]
Liquid | [pka]
3?+-.0.10(Predicted) | [color ]
Colorless to pale yellow | [Sensitive ]
Air Sensitive | [InChI]
1S/C7H7F2NO/c8-7(9)11-6-3-1-2-5(10)4-6/h1-4,7H,10H2 | [InChIKey]
RSOFZRXRIPVBBM-UHFFFAOYSA-N | [SMILES]
Nc1cccc(OC(F)F)c1 | [CAS DataBase Reference]
22236-08-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,T | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Toxic | [HS Code ]
29222990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow liquid | [Uses]
3-(Difluoromethoxy)aniline serves as a synthetic precursor in the preparation of a meta-diamide derivatives by reacting with ethyl acetate, sodium hydrosulfite, tetrabutylammonium hydrogen sulfate, sodium bicarbonate, and heptafluoroisopropyl iodine[1]. | [References]
[1] Wu, D., Li, B., Liu, J., Zhao, T., Xiang, J., & Li, K. (2025). Design, synthesis and insecticidal activities of novel m-diamide compounds containing n-propyl group. Medicinal Chemistry Research, 34(3), 700–708. https://doi.org/10.1007/s00044-025-03374-9 |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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