| Identification | Back Directory | [Name]
Pyrazolo[1,5-a]quinazoline-3-carbonitrile, 2-[1-(4-chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxo- | [CAS]
2226517-75-3 | [Synonyms]
Pyrazolo[1,5-a]quinazoline-3-carbonitrile, 2-[1-(4-chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxo- | [Molecular Formula]
C20H12ClIN4O | [MOL File]
2226517-75-3.mol | [Molecular Weight]
486.69 |
| Chemical Properties | Back Directory | [Boiling point ]
551.3±50.0 °C(Predicted) | [density ]
1.88±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO|9.73|20| | [form ]
Solid | [pka]
10.96±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Dynapyrazole A is a hedgehog signaling inhibitor and dynein inhibitor. | [Uses]
Dynapyrazole A is a specific inhibitor of microtubule dynamin that specifically inhibits the ATPase activity of microtubule-stimulated dynamin without blocking microtubule-independent basal activity[1]. | [storage]
Store at -20°C | [References]
[1] Zhaoyang Jing, et al. Rotavirus Viroplasm Biogenesis Involves Microtubule-Based Dynein Transport Mediated by an Interaction between NSP2 and Dynein Intermediate Chain. J Virol. 2021 Oct 13;95(21):e0124621. DOI:10.1128/JVI.01246-21 |
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