| Identification | Back Directory | [Name]
1-[2-(4-CHLOROPHENYL)-1-(1-HYDROXY-1-PHENYLETHYL)ETHYL]-1,2,4-TRIAZOLE | [CAS]
224047-41-0 | [Synonyms]
BRZ
BRASSINAZOLE
Brassinazole >
(Rac)-Brassinazole
1-[2-(4-Chlorophenyl)-1-(1-hydroxy-1-phenylethyl)e
4-(4-chlorophenyl)-2-phenyl-3-(1,2,4-triazol-1-yl)-2-butanol
4-(4-Chlorophenyl)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)butan-2-ol
3-(4-CHLOROPHENYL)-1-METHYL-1-PHENYL-2-(1,2,4-TRIAZOL-1-YL)-1-PROPANOL
1-[2-(4-CHLOROPHENYL)-1-(1-HYDROXY-1-PHENYLETHYL)ETHYL]-1,2,4-TRIAZOLE
1H-1,2,4-Triazole-1-ethanol, β-[(4-chlorophenyl)methyl]-α-methyl-α-phenyl-
1-[2-(4-Chlorophenyl)-1-(1-hydroxy-1-phenylethyl)ethyl]-1,2,4-triazole
3-(4-Chlorophenyl)-1-methyl-1-phenyl-2-(1,2,4-triazol-1-yl)-1-propanol | [Molecular Formula]
C18H18ClN3O | [MDL Number]
MFCD08276319 | [MOL File]
224047-41-0.mol | [Molecular Weight]
327.81 |
| Chemical Properties | Back Directory | [Boiling point ]
533.1±60.0 °C(Predicted) | [density ]
1.22 | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 100 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 50 mg/ml; Ethanol: 25 mg/ml | [form ]
powder to crystal | [pka]
13.11±0.29(Predicted) | [color ]
White to Yellow to Orange | [InChIKey]
YULDTPKHZNKFEY-UHFFFAOYSA-N | [CAS DataBase Reference]
224047-41-0 |
| Hazard Information | Back Directory | [Uses]
Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole, a triazole derivative, is an inhibitor of brassinosteroid biosynthesis that has been developed in order to probe the myriad functions of brassinosteroids. At 1 μM, it can induce morphological changes, including dwarfism and altered leaf color and curling, in dark-grown Arabidopsis and light-grown cress that are rescued by co-application of a brassinosteroid. | [Definition]
ChEBI: Brassinazole is a member of the class of triazoles that is butan-2-ol which is substituted at positions 2, 3, and 4 by phenyl, 1H-1,2,4-triazol-1-yl and p-chlorophenyl groups, respectively. An inhibitor of brassinosteroid biosynthesis. It has a role as a brassinosteroid biosynthesis inhibitor. It is a member of triazoles, a tertiary alcohol and a member of monochlorobenzenes. | [Enzyme inhibitor]
This triazole-type inhibitor (FW = 327.81; CAS 224047-41-0; Brz2001),
systematically named 4- (4-chlorophenyl) -2-phenyl-3-[[1,2,4]triazol-1-
yl]butan-2-ol, targets brassinosteroid biosynthesis. The latter are plant
steroids and phytohormones that promote organ growth through their
combined effect on cell expansion and division, plant architecture, vascular
differentiation, fertility and flowering, photo-morphogenesis, tolerance to
biotic and abiotic stresses, as well as senescence. Brassinazole’s inhibitory
action is reversed by brassinolide, which showed good recovery after
addition brassinazole-treated plants. Although brassinazole is structurally
similar to pacrobutrazol, a gibberellin biosynthesis inhibitor, it does not
show any evidence of recovery upon addition of gibberellin. Brassinazole
also induces morphological changes in dark-grown Arabidopsis. | [storage]
Store at -20°C |
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