| Identification | Back Directory | [Name]
E3 ligase Ligand 18 | [CAS]
2241669-88-3 | [Synonyms]
E3 ligase Ligand 18
L-Cysteine, N-acetyl-S-[2-amino-9-[(4-chlorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]- | [Molecular Formula]
C17H17ClN6O4S | [MDL Number]
MFCD32263215 | [MOL File]
2241669-88-3.mol | [Molecular Weight]
436.87 |
| Hazard Information | Back Directory | [Uses]
E3 ligase Ligand 18 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 18 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. | [IC 50]
Cereblon | [References]
[1] Heterocyclic compound. WO2018143403A1. |
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