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1957235-99-2

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1957235-99-2 Structure

1957235-99-2 Structure
IdentificationBack Directory
[Name]

Thalidomide-O-C6-NH2 TFA
[CAS]

1957235-99-2
[Synonyms]

Thalidomide-O-C6-NH2 TFA
[Molecular Formula]

C21H24F3N3O7
[MDL Number]

MFCD33398560
[MOL File]

1957235-99-2.mol
[Molecular Weight]

487.43
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Light green to green
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H301-H312-H361
[Precautionary statements ]

P501-P270-P202-P201-P264-P280-P308+P313-P362+P364-P301+P310+P330-P302+P352+P312-P405
Hazard InformationBack Directory
[Uses]

Thalidomide-4-O-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13 (HY-114421), a degrader of FKBP12F36V and BET[1].
[IC 50]

Cereblon
[References]

[1] Erb MA, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 2017 Mar 9;543(7644):270-274. DOI:10.1038/nature21688
Spectrum DetailBack Directory
[Spectrum Detail]

Thalidomide-O-C6-NH2 TFA(1957235-99-2)1HNMR
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