| Identification | Back Directory | [Name]
HYDROXOCOBALAMIN ACETATE | [CAS]
22465-48-1 | [Synonyms]
fresmins
twelvmin
Novidroxin
acetato-cobalami
acetatocobalamin
VITAMIN B12A ACETATE
YDROXOCOBALAMIN ACETATE
HYDROXOCOBALAMIN ACETATE
hydroxocobalamineacetate
VITAMIN B12A ACETATE SALT
HYDROXOCOBALAMIN ACETATE SALT
HYDROXOCOBALAMIN ACETATE, VITAMIN B1
HydroxocobalaMin Acetate (VitaMin B12 Analog)
3’-esterwith5,6-dimethyl-1-alpha-d-ribofuranosylbenzimidazole
cobinamide,acetate(salt)hydroxide,dihydrogenphosphate(ester),innersalt,
Cobinamide Acetate (Salt) Dihydrogen Phosphate (Ester) Inner Salt 3'-Ester with 5,6-Dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
CobinaMide Acetate (Salt) Dihydrogen Phosphate (Ester) Inner Salt 3'-Ester with 5,6-DiMethyl-1-α-D-ribofuranosyl-1H-benziMidazole
Cobinamide, Co-(acetato-.kappa.O)-, dihydrogen phosphate (ester), inner salt, 3-ester with (5,6-dimethyl-1-.alpha.-D-ribofuranosyl-1H-benzimidazole-.kappa.N3) | [EINECS(EC#)]
245-019-7 | [Molecular Formula]
C64H91CoN13O16P- | [MDL Number]
MFCD00082532 | [MOL File]
22465-48-1.mol | [Molecular Weight]
1388.39 |
| Chemical Properties | Back Directory | [Appearance]
Dark-Red Crystalline Powder | [Melting point ]
>3000C. | [storage temp. ]
2-8°C
| [solubility ]
Soluble in water. Some decomposition may occur on drying. | [form ]
Solid | [color ]
Dark Red | [biological source]
synthetic (organic) | [Merck ]
14,4809 | [Major Application]
pharmaceutical | [InChIKey]
QHSPIHUMLGFPKX-BANMRTGHNA-K | [LogP]
-2.812 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Dark-Red Crystalline Powder | [Uses]
Physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound | [General Description]
Hydroxocobalamin is an analog of vitamin B12 with OH as an alkyl group. Vitamin B12 cobalamin refers to a group of chemically-related cobalt containing molecules. | [Biochem/physiol Actions]
Vitamin B12 cobalamin is involved in DNA synthesis and fatty acid synthesis. It also plays a vital role as a coenzyme in the conversion of mitochondrial methylmalonyl co-enzyme A to succinyl co-enzyme A. Vitamin B12 cobalamin is also involved in neurotransmitter synthesis and erythropoiesis. It also functions in the synthesis and maintenance of myelin sheath. Hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. | [Synthesis]
2.4Kg methylcobalamin was prepared into 2000μg/ml methylcobalamin solution, PH was adjusted to 3.18 with 20% acetic acid, air stirring was turned on, and the content of hydroxocobalamin acetate in the reaction solution was 98.3% under the illuminati |
| Safety Data | Back Directory | [WGK Germany ]
3
| [RTECS ]
GG3820000
| [HS Code ]
2936260000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Carc. 2 | [Toxicity]
mouse,LD50,intravenous,2gm/kg (2000mg/kg),Drugs in Japan Vol. 6, Pg. 622, 1982. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
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Spectrum Chemical Manufacturing Corp.
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Sigma-Aldrich
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Kono Chem Co.,Ltd
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www.konochemical.com |
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