| Identification | More | [Name]
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE | [CAS]
22677-21-0 | [Synonyms]
2-PYRROLIDINONE, 4-HYDROXY-, (R)
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE
(R)-4-HYDROXY-2-PYRROLIDINONE
(R)-4-HYDROXY-2-PYRROLIDONE
(R)-BETA-HYDROXY-GAMMA-BUTYROLACTAM
RHPD
(R)-4-hydoroxyoyrolidone
4-hydroxy-R-2-pyrrolidine
(r)-(+)-β-hydroxy-γ-butyrolactam
(r)-β-hydroxy-γ-butyrolactam
2-Pyrrolidinone, 4-hydroxy-, (4R)-
（R)+4-hydroxy-2-prrolidinone
(4R)-4-Hydroxypyrrolidine-2-one
(R)-4β-Hydroxypyrrolidine-2-one
[4R,(-)]-4-Hydroxypyrrolidin-2-one
(R)-4-hydroxy-2-pyrrolidione | [Molecular Formula]
C4H7NO2 | [MDL Number]
MFCD00273364 | [Molecular Weight]
101.1 | [MOL File]
22677-21-0.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
156-160 °C | [Boiling point ]
363.6±35.0 °C(Predicted) | [density ]
1.292±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Sparingly), Methanol (Slightly), Water (Sparingly) | [form ]
Powder | [pka]
13.62±0.20(Predicted) | [color ]
White to pale yellow | [Optical Rotation]
[α]23/D +43°, c = 1 in ethanol | [Water Solubility ]
Slightly soluble in water. | [BRN ]
1524193 | [InChI]
InChI=1S/C4H7NO2/c6-3-1-4(7)5-2-3/h3,6H,1-2H2,(H,5,7)/t3-/m1/s1 | [InChIKey]
IOGISYQVOGVIEU-GSVOUGTGSA-N | [SMILES]
N1C[C@H](O)CC1=O | [CAS DataBase Reference]
22677-21-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R38:Irritating to the skin.
R37:Irritating to the respiratory system.
R36:Irritating to the eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
(R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products. | [Uses]
The (R)-enantiomer intermediate in the preparation of Oxiracetam | [Synthesis]
In a 250mL four-necked flask, add 70mL of water and 2.5mL of triethylamine, stir well, and reduce the temperature to 5~10°C. Add 5g of 2,4-dioxopyrrolidine hydrochloride under stirring, and add 2.77g of potassium borohydride. Add 5g of 2,4-dioxopyrroli |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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