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22862-63-1

22862-63-1 Structure

22862-63-1 Structure
IdentificationBack Directory
[Name]

neoantimycin
[CAS]

22862-63-1
[Synonyms]

neoantimycin
N-(15-Benzyl-10-sec-butyl-14-hydroxy-3-isopropyl-7,13,13-trimethyl-2,5,9,12-tetraoxo-1,4,8,11-tetraoxacyclopentadeca-6-yl)-3-formylamino-2-hydroxybenzamide
Benzamide, 3-(formylamino)-2-hydroxy-N-[(3S,6S,7R,10S,14R,15R)-14-hydroxy-7,13,13-trimethyl-3-(1-methylethyl)-10-[(1S)-1-methylpropyl]-2,5,9,12-tetraoxo-15-(phenylmethyl)-1,4,8,11-tetraoxacyclopentadec-6-yl]-
[Molecular Formula]

C36H46N2O12
[MDL Number]

MFCD11111613
[MOL File]

22862-63-1.mol
[Molecular Weight]

698.76
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
[form ]

White to off-white solid.
Hazard InformationBack Directory
[Uses]

Neoantimycin is a macrocyclic streptomyces antibiotic.
[Uses]

Neoantimycin is a rare and unusual ring-extended member of the antimycin class. Neoantimycin is produced by a Streptomyces species unrelated to antimycin-producing strains. Literature references to neoantimycin are limited but the recent discovery of the closely related metabolite, prunustatin A, as a selective GRP78 molecular chaperone down-regulator highlights the potential of this class as research probes.
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