| Identification | Back Directory | [Name]
Thalidomide-linker 6 | [CAS]
2341840-99-9 | [Synonyms]
halidomide-linker 6
Thalidomide-linker 6
-ether-alkylC2-amine
Thalidomide-O-C2-NH2 hydrochloride
Thalidomide 4'-ether-alkylC2-amine
Thalidomide-linker 6 hydrochloride
Thalidomide 4'-ether-alkylC2-amine (hydrochloride)
4-(2-aminoethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride | [Molecular Formula]
C15H16ClN3O5 | [MDL Number]
MFCD32705128 | [MOL File]
2341840-99-9.mol | [Molecular Weight]
353.76 |
| Hazard Information | Back Directory | [Uses]
Thalidomide-4-O-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. | [IC 50]
Cereblon | [storage]
Store at -20°C | [References]
[1] Turk BE, et al. Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production. Proc Natl Acad Sci U S A. 1996;93(15):7552‐7556. DOI:10.1073/pnas.93.15.7552 |
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