ChemicalBook--->CAS DataBase List--->23599-69-1

23599-69-1

23599-69-1 Structure

23599-69-1 Structure
IdentificationBack Directory
[Name]

norisoboldine
[CAS]

23599-69-1
[Synonyms]

norisoboldine
(+)-Laurelliptine
(+)-Norisoboldine
(+)-N-Norisoboldine
(S)-(+)-Laurelliptine
Norisoboldine, 98%, from Lindera aggregata (Sims) Kosterm.
(6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-4H-dibenzo[de,g]quinoline-1,9-diol
4H-Dibenzo[de,g]quinoline-1,9-diol, 5,6,6a,7-tetrahydro-2,10-dimethoxy-, (6aS)-
[Molecular Formula]

C18H19NO4
[MDL Number]

MFCD09953815
[MOL File]

23599-69-1.mol
[Molecular Weight]

313.35
Chemical PropertiesBack Directory
[Melting point ]

89-191℃
[Boiling point ]

553.0±50.0 °C(Predicted)
[density ]

1.313
[solubility ]

≥ 31.3mg/mL in DMSO
[form ]

Powder
[pka]

9.58±0.20(Predicted)
[color ]

Brown to khaki
Safety DataBack Directory
[Safety Statements ]

24/25
[HS Code ]

29339900
Hazard InformationBack Directory
[Uses]

(+)-Norisoboldine is an anti-arthritis alkaloid isolated from radix linderae which has been shown to attenuate osteoclast differentiation and inflammatory bone erosion in aryl hydrocarbon receptor-dependant manner.
[in vivo]

Norisoboldine (10~40 mg/kg; p.o.; 20 days) significantly reduces the severity of joint swelling and erythema during the course of the experiment[1].
Norisoboldine (40 mg/kg; i.g.; 10 days) induces enhancement of CYP1A1 expression and suppresses expressions of Glut1 and HK2 in colons[2].

Animal Model:Male ICR mice (18–22 g)
Dosage:10~40 mg/kg
Administration:P.o.
Result:Significantly reduced the severity of joint swelling and erythema during the course of the experiment.
Animal Model:Female C57BL/6 mice (18–22 g)
Dosage:40 mg/kg
Administration:I.g.
Result:Induced enhancement of CYP1A1 expression and suppressed expressions of Glut1 and HK2 in colons.
Spectrum DetailBack Directory
[Spectrum Detail]

norisoboldine(23599-69-1)MS
23599-69-1 suppliers list
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Website: www.chemicalbook.com/ShowSupplierProductsList30845/0.htm
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: +86-28-82633860; +8618080483897 , +8618080483897
Website: https://www.phytopurify.com
Company Name: BOC Sciences
Tel: +1-631-485-4226
Website: www.bocsci.com/
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427 , +8618523575427
Website: http://www.conier.com/
Company Name: Wuhan ChemNorm Biotech Co.,Ltd.
Tel: +86-27-8439 4403 18971486879 , 18971486879
Website: www.chemnorm.com
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Hubei Ipure Biology Co., Ltd
Tel: +8613367258412 , +8613367258412
Website: www.ipurechemical.com
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418671 +8618949823763 , +8618949823763
Website: www.tnjchem.com
Company Name: Aktin Chemicals, Inc.
Tel: 028-85159085
Website: www.aktinchem.com
Company Name: Apeloa Pharmaceutical Co., Ltd.
Tel: +86-0571-87635730 +8615858229168 , +8615858229168
Website: www.apeloa.com/en/
Company Name: ANHUI WITOP BIOTECH CO., LTD
Tel: +8615255079626 , +8615255079626
Website: www.chemicalbook.com/showsupplierproductslist418627/0_en.htm
Company Name: Dayang Chem (Hangzhou) Co.,Ltd.
Tel: +86-0571-88938639 +8617705817739 , +8617705817739
Website: www.dycnchem.com/
Company Name: changzhou huayang technology co., ltd
Tel: +8615250961469 , +8615250961469
Website: http://www.huayangchem.com/template/eabout.html
Company Name: TargetMol Chemicals Inc.
Tel:
Website: www.targetmol.com/
Company Name: PT CHEM GROUP LIMITED
Tel: +86-85511178; +86-85511178; , +86-85511178;
Website: https://www.chemicalbook.com/manufacturer/henan-lihao-chem-plant-25020/
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel: 13417589054 , 13417589054
Website: www.chemicalbook.com/ShowSupplierProductsList1962465/0.htm
Company Name: GIHI CHEMICALS CO.,LIMITED
Tel: +8618058761490 , +8618058761490
Website: www.gihichem.com/
Tags:23599-69-1 Related Product Information
13476-25-0 72361-67-2 476-70-0 5890-18-6 11041-94-4 26146-28-1 728-61-0 5843-65-2 26146-27-0

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.