| Identification | Back Directory | [Name]
Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)- | [CAS]
2361972-29-2 | [Synonyms]
Succinate/succinate receptor antagonist 1
2-(4-(1,8-naphthyridin-2-yl)phenyl)-N-methylacetamide
Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)- | [Molecular Formula]
C17H15N3O | [MOL File]
2361972-29-2.mol | [Molecular Weight]
277.33 |
| Chemical Properties | Back Directory | [Boiling point ]
546.5±50.0 °C(Predicted) | [density ]
1.202±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
15.73±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Succinate/succinate receptor antagonist 1 (compound 7a) is a succinate/succinate receptor antagonist. Succinate/succinate receptor antagonist 1 blocks succinate signaling in gingival tissue. Succinate/succinate receptor antagonist 1 inhibits the activation of succinate receptor 1 (SucnRl) with an IC50 value of 20 μΜ. Succinate/succinate receptor antagonist 1 can be used for the research of periodontal disease[1]. | [References]
[1] LI, Xin, et al. PERIODONTAL DISEASE THERAPY. WO2019136022. 2020. |
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