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236426-37-2

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236426-37-2 Structure

236426-37-2 Structure
IdentificationBack Directory
[Name]

Fmoc-Gly-Gly-Phe-OtBu
[CAS]

236426-37-2
[Synonyms]

Fmoc-Gly-Gly-Phe-OtBu
L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-, 1,1-dimethylethyl ester
[Molecular Formula]

C32H35N3O6
[MDL Number]

MFCD32689552
[MOL File]

236426-37-2.mol
[Molecular Weight]

557.64
Chemical PropertiesBack Directory
[Boiling point ]

806.7±65.0 °C(Predicted)
[density ]

1.222±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

10.61±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Cleavable Linker
[References]

[1] Bak A, et al. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker. J Pept Res. 1999 Apr;53(4):393-402. DOI:10.1034/j.1399-3011.1999.00070.x
Spectrum DetailBack Directory
[Spectrum Detail]

Fmoc-Gly-Gly-Phe-OtBu(236426-37-2)1HNMR
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