ChemicalBook--->CAS DataBase List--->2375105-86-3

2375105-86-3

2375105-86-3 Structure

2375105-86-3 Structure
IdentificationBack Directory
[Name]

Cyanine5.5 NHS ester
[CAS]

2375105-86-3
[Synonyms]

Cyanine5.5 NHS ester (BF4)
[Molecular Formula]

C44H46BF4N3O4
[MOL File]

2375105-86-3.mol
[Molecular Weight]

767.67
Chemical PropertiesBack Directory
[solubility ]

soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
[Appearance]

dark blue to violet solid
[InChIKey]

QJHUOARMFFEDJW-UHFFFAOYSA-N
[SMILES]

[B+3]([F-])([F-])([F-])[F-].CC1(C(N(CCCCCC(=O)ON2C(CCC2=O)=O)C2C=CC3=CC=CC=C3C1=2)=CC=CC=CC1=[N+](C2C=CC3=CC=CC=C3C=2C1(C)C)C)C
Hazard InformationBack Directory
[Description]

Cyanine5.5 NHS ester is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides, an analog of Cy5.5® NHS ester.


Cy5.5 is a far-red (and near-infrared) emitting dye which is ideal for fluorescence measurements where background fluorescence is a concern. It is also suitable for in vivo NIR imaging experiments.


This reagent can replace NHS esters of Cy5.5® and DyLight 680.

[Uses]

Cyanine5.5 NHS ester tetrafluoroborate belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
[References]

[1] Armitage B A. Cyanine dye–DNA interactions: intercalation, groove binding, and aggregation[J]. DNA Binders and Related Subjects: -/-, 2005: 55-76.
[Abs/Em Maxima]

684/710 nm
[Fluoresene quantum yield]

0.2
[Extinction Coefficient]

198000
[CF260]

0.07
[CF280]

0.03
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