| Identification | Back Directory | [Name]
H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT | [CAS]
23815-87-4 | [Synonyms]
RPPGFSP
1-7-Bradykinin
BRADYKININ (1-7)
BRADYKININ 1-7 ACETATE
BRADYKININ FRAGMENT 1-7
ARG-PRO-PRO-GLY-PHE-SER-PRO
[Des-Phe8-des-Arg9]bradykinin
Arg-Pro-Pro-Gly-Phe-Ser-Pro-OH
des-phe(8)-des-arg(9)-bradykini
H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-OH
bradykinin, des-Phe(8)-des-Arg(9)-
ARG-PRO-PRO-GLY-PHE-SER-PRO ACETATE
Bradykinin Fragment 1-7, ≥97% (HPLC)
H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACOH
L-Arg-L-Pro-L-Pro-Gly-L-Phe-L-Ser-L-Pro-OH
BRADYKININ FRAGMENT 1-7, MASS SPEC STANDARD
H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT
4: PN: WO2005057221 PAGE: 17 unclaimed sequence
ProteoMass? Bradykinin Fragment 1-7 MALDI-MS Standard
H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT USP/EP/BP
ProteoMassTM Bradykinin Fragment 1-7 MALDI-MS Standard
Bradykinin (1-7) acetate salt H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-OH acetate salt
N5-(Diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-proline | [Molecular Formula]
C35H52N10O9 | [MDL Number]
MFCD00237801 | [MOL File]
23815-87-4.mol | [Molecular Weight]
756.85 |
| Chemical Properties | Back Directory | [density ]
1.522±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
−20°C
| [solubility ]
Soluble in DMSO | [form ]
Powder | [pka]
3.327±0.20(predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble in water (1 mg/ml). | [Sequence]
Arg-Pro-Pro-Gly-Phe-Ser-Pro | [InChIKey]
CRROPKNGCGVIOG-UHFFFAOYSA-N | [SMILES]
NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(CO)C(=O)N4CCCC4C(O)=O |
| Hazard Information | Back Directory | [Uses]
Bradykinin Fragment 1-7 is used in research on the specificity and kinetics of kininase(s). Bradykinin dilates blood vessels via the release of prostacyclin, nitric oxide, and Endothelium Derived Hyperpolarizing Factor. Bradykinin is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino acids. | [Definition]
ChEBI:[des-Phe(8), des-Arg(9)]-bradykinin is a seven-membered oligopeptide comprising Arg, Pro, Pro, Gly, Phe, Ser, and Pro residues joined in sequence by peptide bonds. It is a metabolite of bradykinin lacking the Phe residue at position 8 and the Arg residue at position 9. It has a role as a human metabolite and a rat metabolite. It is a conjugate base of a [des-Phe(8), des-Arg(9)]-bradykinin(1+). | [Biological Activity]
Bradykinin (BK) is a pro-inflammatory mediator and a neuromediator. It modulates several vascular and renal functions. Bradykinin (BK) plays a key role in inducing vascular permeability and mitogenesis. It helps to activate the liberation of nitric oxide in inflammatory and cancer tissues. | [storage]
Store at -20°C |
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