| Identification | More | [Name]
N,N'-DICYCLOHEXYLUREA | [CAS]
2387-23-7 | [Synonyms]
1,3-DICYCLOHEXYLUREA
AURORA KA-3582
CYCLOHEXYLUREA
DCU
N,N'-DICYCLOHEXYLUREA
n,n’-dicyclohexyl-ure
N,N,-Dicyclohexylurea98.%
Dicyclohexylcarbodiamide
N,N'-Carbonylbis(cyclohexanamine) | [EINECS(EC#)]
219-213-7 | [Molecular Formula]
C13H24N2O | [MDL Number]
MFCD00003829 | [Molecular Weight]
224.34 | [MOL File]
2387-23-7.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
R22:Harmful if swallowed.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29242100 |
| Hazard Information | Back Directory | [Chemical Properties]
white crystalline powder | [Uses]
N,N''-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C. | [Definition]
ChEBI: 1,3-dicyclohexylurea is a member of ureas. | [Preparation]
An excess of dry ice (200 g) was added gradually to a solution of dicyclohexylcarbodiimide (2.06 g, 0.01 mol), cyclohexylamine (1.98 g, 0.02 mol), and triethylamine (2.2 g, 0.02 mol) in THF at 75 ℃ over a period of 8 h. After stirring for 8 h, the reaction mixture was concentrated under reduced pressure and the resultant precipitate was collected. Fractional recrystallization of the precipitate from acetone/methanol gave N,N'-dicyclohexylurea; yield 2.2 g (98% based on dicyclohexylcarbodiimide and cyclohexylamine). | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 61, p. 4175, 1996 DOI: 10.1021/jo9522825 | [storage]
Store at -20°C |
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