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23887-46-9

23887-46-9 Structure

23887-46-9 Structure
IdentificationMore
[Name]

Cinepazide
[CAS]

23887-46-9
[Synonyms]

1-(pyrrolidin-1-ylcarbonylmethyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine
CINEPAZIDE
PIPERAZINE,1-[2-OXO-2-(1-PYRROLIDINYL)ETHYL]-4-[1-OXO-3-(3,4,5-TRIMETHOXYPHENYL)-2-PROPENYL]
1-(1-Pyrrolidinylcarbonylmethyl)-4-[3-(3,4,5-trimethoxyphenyl)acryloyl]piperazine
1-[(1-Pyrrolidinylcarbonyl)methyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]piperazine
[EINECS(EC#)]

245-928-9
[Molecular Formula]

C22H31N3O5
[MDL Number]

MFCD00868266
[Molecular Weight]

417.5
[MOL File]

23887-46-9.mol
Chemical PropertiesBack Directory
[Boiling point ]

637.8±55.0 °C(Predicted)
[density ]

1.200±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

5.22±0.10(Predicted)
[CAS DataBase Reference]

23887-46-9(CAS DataBase Reference)
Hazard InformationBack Directory
[Uses]

Cinepazide is an injection in the treatment of acute myocardial infarction and its effect on serum inflammatory factors.
[Definition]

ChEBI: Cinepazide is an olefinic compound. It is functionally related to a cinnamic acid.
[World Health Organization (WHO)]

Cinepazide, a vasodilating agent, was first introduced into medicine in 1974. It is used in the treatment of peripheral and cerebral vascular disorders. Following reports of blood dyscrasias, including agranulocytosis and thrombocytopenia, associated with the use of the drug, the Spanish Committee on Drug Surveillance has recommended its withdrawal. In other countries, the approved product information of preparations containing cinepazide has been amended to include a relevant warning on these adverse effects.
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