| Identification | Back Directory | [Name]
2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl | [CAS]
240417-00-9 | [Synonyms]
PhDavePhos
PhDave-Phos 97%
2-Diphenylphosphino-2
(N,N-DIMETHYLAMINO)BIPHENYL
2-Diphenylphosphino-2'-(N,N-di
2-Diphenylphosphino-2`-dimethylaminobiphenyl
2-DIMETHYLAMINO-2'-(DIPHENYLPHOSPHINO)BIPHENYL
2-Dimethylamino-2'-(diphenylphosphino)biphenyl
2-DiphenylphosphiNA-2'-(N,N-diMethylaMiNA)biphenyl
2-[2-(diphenylphosphanyl)phenyl]-N,N-diMethylaniline
2-(DIPHENYLPHOSPHINO)-2'-(N,N-DIMETHYLAMINO)BIPHENYL
2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl,98%
2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl,97%
2′-(Diphenylphosphino)-N,N′-dimethyl-(1,1′-biphenyl)-2-amine
2-Diphenylphosphino-2'-(N,N-diMethylaMino)biphenyl PhDavePhos
[1,1''-BIPHENYL]-2-AMINE, 2''-(DIPHENYLPHOSPHINO)-N,N-DIMETHYL-
2-Diphenylphosphino-2'-(N,N-diMethylaMino)biphenyl, 98% (PhDavePhos)
2-Diphenylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% PhDavePhos
2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl (This product is only available in Japan.) | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C26H24NP | [MDL Number]
MFCD03094578 | [MOL File]
240417-00-9.mol | [Molecular Weight]
381.45 |
| Chemical Properties | Back Directory | [Appearance]
white to yellow powder, crystals, crystalline | [Melting point ]
126-128 °C
| [Boiling point ]
514.6±43.0 °C(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
Powder, Crystals, Crystalline Powder and/or Chunks | [pka]
4.96±0.18(Predicted) | [color ]
White to yellow | [Water Solubility ]
insoluble | [InChIKey]
JGFXUYLYPITYGR-UHFFFAOYSA-N | [CAS DataBase Reference]
240417-00-9 |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellow powder, crystals, crystalline | [Uses]
suzuki reaction | [reaction suitability]
reaction type: Cross Couplings
reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reagent type: ligand
reaction type: C-C Bond Formation | [Synthesis]
The compound (CAS:119326-02-2) (29.6 mg, 0.0510 mmol) was transferred to an argon protected 10 mL Schlenk flask. The flask was evacuated and filled with argon three times to remove air. Subsequently, anhydrous THF (3.0 mL) was added using a syringe under argon atmosphere. A THF solution (0.46 mL, 0.23 mmol) of 0.5 M LiPPh2 was slowly added dropwise under stirring for a controlled time of 5 min. During the reaction, the color of the mixture changed from yellow to dark red and finally to dark yellow. The reaction mixture was stirred under argon protection at room temperature for 18 hours. After completion of the reaction, the solvent was removed using a rotary evaporator. The crude product was dissolved in dichloromethane (0.5 mL) and purified by preparative thin layer chromatography (silica gel, unfolding reagent was benzene:acetone=10:1). The final isolation afforded the target product (S)-2-diphenylphosphino-2'-(N,N-dimethylamino)biphenyl as a light yellow liquid in 46% yield (15.6 mg). | [References]
[1] Journal of Organometallic Chemistry, 2013, vol. 745-746, p. 356 - 362 |
| Questions And Answer | Back Directory | [Reaction]
- Useful ligand for sterically hindered substrates in the Pd-catalyzed amination reactions of aryl bromides.
- Ligand used for the Cu-catalyzed phosphorylation of alcohols.
- Ligand for Pd-catalyzed C-H benzylation.
- Ligand for palladium-catalyzed [4 + 2] benzannulation reaction.
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
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400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
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0086-21-58956006 |
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www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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