| Identification | More | [Name]
3-Dimethylaminopropylamine | [CAS]
109-55-7 | [Synonyms]
1-Amino-3-dimethylaminopropane
3-DIMETHYLAMINO-1-PROPYLAMINE
3-DIMETHYLAMINO-N-PROPYLAMINE
3-DIMETHYLAMINOPROPYLAMINE
DIMETHYLAMINOPROPYLAMINE
DMAPA
N,N-DIMETHYL-1,3-DIAMINOPROPANE
N,N-DIMETHYL-1,3-PROPANEDIAMINE
N,N-DIMETHYL PROPANE-1,3-DIAMINE
N,N-DIMETHYLTRIMETHYLENEDIAMINE
RARECHEM AL BW 0072
1-(Dimethylamino)-3-aminopropane
1,3-propanediamine,N,N-dimethyl-
1-dimethylamino-3-aminopropane
3-(Dimethylamino)-1-propanamine
3-(n,n-dimethylamino)-propylamin
3-Amino-1-(dimethylamino)propane
3-Propanediamine,N,N-dimethyl-1
-Dimethylamino
gamma-(Dimethylamino)propylamine | [EINECS(EC#)]
203-680-9 | [Molecular Formula]
C5H14N2 | [MDL Number]
MFCD00008216 | [Molecular Weight]
102.18 | [MOL File]
109-55-7.mol |
| Chemical Properties | Back Directory | [Appearance]
clear liquid | [Melting point ]
-60 °C
| [Boiling point ]
133 °C(lit.)
| [density ]
0.812 g/mL at 25 °C(lit.)
| [vapor density ]
3.6 (vs air)
| [vapor pressure ]
5 mm Hg ( 20 °C)
| [refractive index ]
n20/D 1.435(lit.)
| [Fp ]
90 °F
| [storage temp. ]
Flammables area | [form ]
Liquid | [pka]
10.13±0.10(Predicted) | [color ]
Clear | [Odor]
ammoniacal odor | [PH]
12.7 (100g/l, H2O, 20℃) | [explosive limit]
2.3-12.35%(V) | [Water Solubility ]
SOLUBLE | [FreezingPoint ]
-70℃ | [Sensitive ]
Air Sensitive | [BRN ]
605293 | [Contact allergens]
Dimethylaminopropylamine is an aliphatic amine present in amphoteric surfactants such as liquid soaps and shampoos. It is present as a residual impurity thought to be responsible for allergy from cocamidopropylbetaine. It is structurally similar to diethylaminopropylamine. It is also used as a curing agent for epoxy resins and an organic intermediate in chemical synthesises (ion exchangers, additives for flocculants, cosmetics and fuel additives, dyes and pesticides). Patch test has to be carefully interpreted, since the 1% aqueous solution has pH > 11 (personal observation). | [InChIKey]
IUNMPGNGSSIWFP-UHFFFAOYSA-N | [LogP]
-0.352 at 25℃ | [CAS DataBase Reference]
109-55-7(CAS DataBase Reference) | [NIST Chemistry Reference]
1,3-Propanediamine, N,N-dimethyl-(109-55-7) | [Storage Precautions]
Store under nitrogen | [EPA Substance Registry System]
109-55-7(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
clear liquid | [Uses]
N,N-Dimethyl-1,3-propylenediamine is a useful catalyst for Knoevenagel condensation. It is also a useful hardening agent for expoxy resin. | [General Description]
Colorless liquid. | [Reactivity Profile]
DIMETHYLAMINOPROPYLAMINE(109-55-7) neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. | [Air & Water Reactions]
Highly flammable. Temperature sensitive and possibly sensitive to air. Water soluble. | [Fire Hazard]
This compound is flammable. | [Description]
Dimethylaminopropylamine is an aliphatic amine
present in amphoteric surfactants such as liquid soaps
and shampoos. It is present as an impurity responsible
for allergy from cocamidopropylbetaine. It is structurally
similar to diethylaminopropylamine. It is also used
as a curing agent for epoxy res ins and as an organic
intermediate in chemical syntheses (ion exchangers,
additives for flocculants, cosmetics and fuel additives,
dyes and pesticides).
| [Production Methods]
3-Dimethylaminopropylamine is produced by addition of dimethylamine to acrylonitrile and subsequent hydrogenation in the presence of ammonia.
| [Flammability and Explosibility]
Flammable | [Toxicology]
There are indications of contact and possibly respiratory allergy in relation to occupational exposure. Less than 0.9 ppm of 3-dimethylaminopropylamine in the workplace air may adversely affect respiratory function. The skin-sensitizing potential was verified in an animal study. In an oral 28-d study with rats (gavage, 7 times per week.), clinical symptoms including pulmonary and cardiac failure were noted at 250 mg kg -1 d -1, but no treatment-related effects at a level of 50 mg kg -1 d -1.
|
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R10:Flammable.
R22:Harmful if swallowed.
R34:Causes burns.
R43:May cause sensitization by skin contact. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2733 3/PG 3
| [WGK Germany ]
2
| [RTECS ]
TX7525000
| [Autoignition Temperature]
215 °C | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29212900 | [Safety Profile]
Moderately toxic by ingestion and skin contact. A skin and eye irritant. Very flammable when exposed to heat, flame, or oxidmers. Reaction with 1,2dichloroethane produces explosive acetylene gas. This and other amines igmte on contact with cellulose nitrate of hgh surface area. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NO,. See also AMINES | [Hazardous Substances Data]
109-55-7(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 1640 mg/kg |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Hydrogen-->Dimethylamine-->Dimethylaminopropionitrile-->HYDROGENATION CATALYST-->1-Propanol, 3-amino-,1-(hydrogen sulfate)-->1H-Isoindole-1,3(2H)-dione, 2-[3-(dimethylamino)propyl]--->3-(DIMETHYLAMINO)ACRYLONITRILE-->N,N-Dimethylaminopropyl acrylamide-->N-METHYL-1,3-PROPANEDIAMINE-->N,N'-Dimethyl-1,3-propanediamine-->ALPHA-DIMETHYLAMINOPROPIONITRILE-->3,3'-IMINOBIS(N,N-DIMETHYLPROPYLAMINE) | [Preparation Products]
1-(3-DIMETHYLAMINOPROPYL)-3-ETHYLCARBODIIMIDE METHIODIDE-->1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide-->N-[3-(dimethylamino)propyl]myristamide-->SEC-BUTYL ETHER-->N'-(2-Methoxybenzyl)-N,N-dimethylpropane-1,3-diamine |
|
|