2409969-94-2

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2409969-94-2 Structure

Identification	Back Directory
[Name] m-PEG10-acid
[CAS] 2409969-94-2
[Synonyms] m-PEG10-acid Methyl-PEG9-acid
[Molecular Formula] C22H44O12
[MDL Number] MFCD27977513
[MOL File] 2409969-94-2.mol
[Molecular Weight] 500.58

Hazard Information	Back Directory
[Uses] m-PEG10-acid is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
[IC 50] PEGs; Non-cleavable Linker
[References] [1] John F. Donovan et al. Pegylated prodrugs of phenolic trpv1 agonists. WO2020023794A1. [2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

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