| Chemical Properties | Back Directory | [Boiling point ]
568.3±50.0 °C(Predicted) | [density ]
1.112±0.06 g/cm3(Predicted) | [form ]
Oil | [pka]
4.28±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
m-PEG10-acid is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. | [IC 50]
PEGs; Non-cleavable Linker | [References]
[1] John F. Donovan et al. Pegylated prodrugs of phenolic trpv1 agonists. WO2020023794A1.
[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
|
| Company Name: |
LAURENT.INC Gold
|
| Tel: |
17721037897 |
| Website: |
laurentpeg.com/ |
|