| Identification | Back Directory | [Name]
m-PEG9-bromide | [CAS]
125562-30-3 | [Synonyms]
mPEG9-Br
m-PEG9-bromide
Bromo-PEG9-methoxy
Methyl-PEG9-bromide, M-Peg9-bromide, MPEG9-BR
28-Bromo-2,5,8,11,14,17,20,23,26-nonaoxaoctacosane
2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane, 28-bromo- | [Molecular Formula]
C19H39BrO9 | [MDL Number]
MFCD28950767 | [MOL File]
125562-30-3.mol | [Molecular Weight]
491.41 |
| Chemical Properties | Back Directory | [Boiling point ]
498.1±40.0 °C(Predicted) | [density ]
1.190±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Liquid | [color ]
Yellow to brown |
| Hazard Information | Back Directory | [Description]
m-PEG9-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG9-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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