| Identification | More | [Name]
L-Glutamic acid 5-tert-butyl ester | [CAS]
2419-56-9 | [Synonyms]
GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER MONOHYDRATE
GLUTAMIC ACID(OTBU)-OH
H-GLU(OBUT)-OH
H-GLU(OTBU)-OH
H-GLU(OTBU)-OH H2O
H-L-GLU(TBU)-OH H2O
L-GAMMA-T-BUTYL GLUTAMATE
L-GLUTAMIC ACID 5-TERT-BUTYL ESTER
L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER
L-GLUTAMIC ACID-GAMMA-T-BUTYL ESTER MONOHYDRATE
Glu(OtBu)-OH
L-Glutamic acid γ-tert·butyl ester monohydrate
L-Glutamic acid 5-t-Butyl Ester
GLUTAMIC ACID GAMMA-T-BUTYL ESTER MONOHYDRATE
L-GLUTAMIC ACID-Y-T-BUTYL ESTER
L-GLUTAMIC ACID-Y-T-BUTYLESTER MONOHYDRATE
L-GLUTAMIC ACID .GAMMA.-TERT-BUTYL ESTER MONOHYDRATE
L-Glutamic acid γ-t.-butyl ester | [EINECS(EC#)]
247-005-6 | [Molecular Formula]
C9H17NO4 | [MDL Number]
MFCD00270551 | [Molecular Weight]
203.24 | [MOL File]
2419-56-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
182°C(lit.) | [Boiling point ]
110 °C(Press: 0.05 Torr) | [density ]
0.992 g/cm3 | [storage temp. ]
2-8°C
| [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Solid | [pka]
2.20±0.10(Predicted) | [color ]
White to Almost white | [Water Solubility ]
Sparingly soluble in water; practically insoluble in ethanol or ether. | [BRN ]
2049031 | [InChI]
InChI=1S/C9H17NO4/c1-9(2,3)14-7(11)5-4-6(10)8(12)13/h6H,4-5,10H2,1-3H3,(H,12,13)/t6-/m0/s1 | [InChIKey]
OIOAKXPMBIZAHL-LURJTMIESA-N | [SMILES]
C(O)(=O)[C@H](CCC(OC(C)(C)C)=O)N | [CAS DataBase Reference]
2419-56-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Risk Statements ]
22-24 | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29224999 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder crystal | [Uses]
L-Glutamic acid 5-tert-butyl ester is used as a fine chemical intermediate, pharmaceutical intermediate. | [reaction suitability]
reaction type: solution phase peptide synthesis | [Synthesis]
In a 3000mL three-necked flask, 2324g of tert-butyl acetate and 73.5g of glutamic acid were added, stirred, and was added dropwise.
160.8 mL of perchloric acid, react for 48 hours at 10°C, cool down to 0°C, add 1000 mL of water, extract
(the remainin |
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