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2446817-72-5

2446817-72-5 Structure

2446817-72-5 Structure
IdentificationBack Directory
[Name]

1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-
[CAS]

2446817-72-5
[Synonyms]

APOL1-IN-1
1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-
[Molecular Formula]

C21H20FN3O3
[MOL File]

2446817-72-5.mol
[Molecular Weight]

381.4
Chemical PropertiesBack Directory
[Boiling point ]

801.4±65.0 °C(Predicted)
[density ]

1.40±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 125 mg/mL (327.74 mM; Need ultrasonic)
[form ]

Solid
[pka]

13.03±0.40(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD)[1].
[Biological Activity]

APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD)[1].
[storage]

Store at -20°C
[References]

[1]. Brodney M, et, al. Inhibitors of apol1 and methods of using same. WO2020131807A1.
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