| Identification | Back Directory | [Name]
N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite | [CAS]
251647-54-8 | [Synonyms]
2'-O-MOE-Bz-C Phosphoramidite
2'-O-MOE-rC(Bz) Phosphoramidite
2'-O-MOE-C(Bz)-CE Phosphoramidite
2'-O-MOE-C(Bz)-3'-phosphoramidite
DMT-2'-O-MOE-C(Bz)-CE-Phosphoramidite
N4-Bz-5’-O-DMTr-2’-O-(2-methoxyethyl)cytidine-3’-CED-phosphoramidite
N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite
N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite
5'-O-DMT-N4-Benzoyl-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite
N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-cyanoethyl Phosphoramidite
N4-Acetyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-Methylcytidine-3'- CE-cyanoethyl Phosphoramidite
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)cytidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) | [Molecular Formula]
C49H58N5O10P | [MDL Number]
MFCD15145377 | [MOL File]
251647-54-8.mol | [Molecular Weight]
908 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
8.57±0.20(Predicted) | [color ]
White to light yellow | [InChIKey]
IAFVTVZPQIFRAU-STEDOTHVNA-N | [SMILES]
C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=CC(NC(C3C=CC=CC=3)=O)=NC2=O)[C@H](OCCOC)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,44,50,r| |
| Hazard Information | Back Directory | [Uses]
2'-O-MOE-rC is a 2'-O-MOE modified nucleoside. 2'-O-MOE-rC can be used for synthesis of DNA[1][2]. | [References]
[1] Prakash TP, et al. Comparing in vitro and in vivo activity of 2'-O-[2-(methylamino)-2-oxoethyl]- and 2'-O-methoxyethyl-modified antisense oligonucleotides. J Med Chem. 2008 May 8;51(9):2766-76. DOI:10.1021/jm701537z
[2] Li M, et al. Synthesis and cellular activity of stereochemically-pure 2'-O-(2-methoxyethyl)-phosphorothioate oligonucleotides. Chem Commun (Camb). 2017 Jan 3;53(3):541-544. DOI:10.1039/c6cc08473g |
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