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254-60-4

254-60-4 Structure

254-60-4 Structure
IdentificationMore
[Name]

1,8-NAPHTHYRIDINE
[CAS]

254-60-4
[Synonyms]

1, 8 - nalidixic
1,8-NAPHTHYRIDINE
1,8-Pyridopyridine
1,8-Diazanapthalene
1,8-DIAZANAPHTHALENE
1,8-Naphthyridine>
PYRIDO[2,3-B]PYRIDINE
1,8-NAPHTHYRIDINE 98+%
1,8-Diazanaphthalene 98%
1,8-Naphthyridine(6CI,7CI,8CI,9CI)
1,8-NAPHTHYRIDINE ISO 9001:2015 REACH
1,8-Diazanaphthalene Pyrido[2,3-b]pyridine
[Molecular Formula]

C8H6N2
[MDL Number]

MFCD00059751
[Molecular Weight]

130.15
[MOL File]

254-60-4.mol
Chemical PropertiesBack Directory
[Melting point ]

99.8-99.9°C
[Boiling point ]

248.9±13.0 °C(Predicted)
[density ]

1.183±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[form ]

powder to crystal
[pka]

3.55±0.10(Predicted)
[color ]

White to Light yellow to Light orange
[InChI]

InChI=1S/C8H6N2/c1-3-7-4-2-6-10-8(7)9-5-1/h1-6H
[InChIKey]

FLBAYUMRQUHISI-UHFFFAOYSA-N
[SMILES]

N1C2C(=CC=CN=2)C=CC=1
[CAS DataBase Reference]

254-60-4(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[WGK Germany ]

WGK 3
[HazardClass ]

IRRITANT
[HS Code ]

2902900000
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Eye Dam. 1
Raw materials And Preparation ProductsBack Directory
[Preparation Products]

Nalidixic acid
Hazard InformationBack Directory
[Description]

1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.
[Uses]

1,8-naphthyridine (napy) and its simplest 2-methyl and 2,7-dimethyl derivatives may act as monodentate and bidentate ligands, resembling the behavior of the carboxylate ligands.
[Definition]

ChEBI: A naphthyridine in which the nitrogens are situated at positions 1 and 8.
[Purification Methods]

Purify 1,8-naphthyridine through an Al2O3 column and elute with toluene and pet ether, evaporate the eluate, crystallise the residue from pet ether (b 60-80o), and sublime it at 80o/13mm. The picrate [15936-16-0] has m 207-208o (from EtOH), and the methiodide has m 180-181o (from EtOH). [Hawes & Wibberley J Chem Soc (C) 1564 1967, UV: Armarego Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 134 1971, Beilstein 23 II 178, 23 III/IV 1237.]
Spectrum DetailBack Directory
[Spectrum Detail]

1,8-NAPHTHYRIDINE(254-60-4)MS
1,8-NAPHTHYRIDINE(254-60-4)1HNMR
1,8-NAPHTHYRIDINE(254-60-4)13CNMR
1,8-NAPHTHYRIDINE(254-60-4)IR1
1,8-NAPHTHYRIDINE(254-60-4)IR2
1,8-NAPHTHYRIDINE(254-60-4)ESR
Well-known Reagent Company Product InformationBack Directory
[TCI AMERICA]

1,8-Naphthyridine,>98.0%(GC)(T)(254-60-4)
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