| Identification | More | [Name]
1,8-NAPHTHYRIDINE | [CAS]
254-60-4 | [Synonyms]
1, 8 - nalidixic
1,8-NAPHTHYRIDINE
1,8-Pyridopyridine
1,8-Diazanapthalene
1,8-DIAZANAPHTHALENE
1,8-Naphthyridine>
PYRIDO[2,3-B]PYRIDINE
1,8-NAPHTHYRIDINE 98+%
1,8-Diazanaphthalene 98%
1,8-Naphthyridine(6CI,7CI,8CI,9CI)
1,8-NAPHTHYRIDINE ISO 9001：2015 REACH
1,8-Diazanaphthalene
Pyrido[2,3-b]pyridine | [Molecular Formula]
C8H6N2 | [MDL Number]
MFCD00059751 | [Molecular Weight]
130.15 | [MOL File]
254-60-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
99.8-99.9°C | [Boiling point ]
248.9±13.0 °C(Predicted) | [density ]
1.183±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
3.55±0.10(Predicted) | [color ]
White to Light yellow to Light orange | [InChIKey]
FLBAYUMRQUHISI-UHFFFAOYSA-N | [CAS DataBase Reference]
254-60-4(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones. | [Uses]
1,8-naphthyridine (napy) and its simplest 2-methyl and 2,7-dimethyl derivatives may act as monodentate and bidentate ligands, resembling the behavior of the carboxylate ligands. | [Definition]
ChEBI: A naphthyridine in which the nitrogens are situated at positions 1 and 8. | [Purification Methods]
Purify 1,8-naphthyridine through an Al2O3 column and elute with toluene and pet ether, evaporate the eluate, crystallise the residue from pet ether (b 60-80o), and sublime it at 80o/13mm. The picrate [15936-16-0] has m 207-208o (from EtOH), and the methiodide has m 180-181o (from EtOH). [Hawes & Wibberley J Chem Soc (C) 1564 1967, UV: Armarego Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 134 1971, Beilstein 23 II 178, 23 III/IV 1237.] |
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