| Identification | More | [Name]
Propidium iodide | [CAS]
25535-16-4 | [Synonyms]
3,8-DIAMINO-5-(3-DIETHYLAMINOPROPYL)-6-PHENYLPHENANTHRIDINIUM IODIDE METHIODIDE
3,8-DIAMINO-5-(3-DIETHYL-AMINOPROPYL)-6-PHENYLPHENANTHRIDIUM IODIDE METHIODIDE
3,8-DIAMINO-5-(3-[DIETHYLMETHYLAMMONIO])-6-PHENYLPHENAN-THRIDINIUM DIIODIDE
3,8-DIAMINO-5-[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYLPHENANTHRIDINIUM
3,8-DIAMINO-5-[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYLPHENANTHRIDINIUM DIIODIDE
PHENANTHRIDINIUM, 3,8-DIAMINO-5-[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYL-, DIIODIDE
PI
PROPIDIUM IODIDE
3,8-diamino-5-(3-(diethylmethylammonio)propyl)-6-phenyl-phenanthridiniudii
3,8-diamino-5-(3-(diethylmethylammonio)propyl)-6-phenylphenanthridiniumdiiod
3,8-diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridiniumiodidemethiodi
Propidium iodide solution
Propidium diiodide
PROPIDIUM IODIDE 95-98%
PROPIDIUM IODIDE, FOR FLUORESCENCE
PROPIDIUM IODIDE 95%
-Cellstain-PiSolution
-Cellstain-Pi
PROPIDIUM IODIDE RED POWDER
3,8-Diamino-5-[3-(diethylmethylamino)propyl]-6-phenylphenanthridium,diiodide | [EINECS(EC#)]
247-081-0 | [Molecular Formula]
C27H34I2N4 | [MDL Number]
MFCD00011921 | [Molecular Weight]
668.39 | [MOL File]
25535-16-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
220-225 °C (dec.) (lit.) | [density ]
1.5072 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
Difficult to mix. | [form ]
Flaky Powder | [color ]
Dark red | [Appearance]
Red solid or powder | [Water Solubility ]
Soluble in water at 1mg/ml | [ex/em]
535/617 nm (and DNA) | [Sensitive ]
Light Sensitive & Hygroscopic | [Usage]
A phenanthridine compound, a class of compounds with reported activity against several species of trypanosomes | [ε(extinction coefficient)]
5400 cm−1M−1 (water/DNA) | [λmax]
493 nm, 535 nm | [BRN ]
3843838 | [Biological Applications]
Detecting nucleic acids,cancer cells,spores,activity of hydrolase,microorganisms; apoptosis assay; measuring beta-amyloid in Alzheimer’s disease (AD); treating diseases associated with androgens,cancer | [Major Application]
Electroluminescent
displays; photoresists | [InChIKey]
ISKCJFFZOPXOFC-UHFFFAOYSA-N | [SMILES]
C([N+]1=C2C=C(N)C=CC2=C2C=CC(N)=CC2=C1C1C=CC=CC=1)CC[N+](C)(CC)CC.[I-] | [CAS DataBase Reference]
25535-16-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS08 | [Signal word ]
Warning | [Hazard statements ]
H341 | [Precautionary statements ]
P201-P202-P280-P308+P313-P405-P501 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S22:Do not breathe dust . | [WGK Germany ]
3 | [RTECS ]
SF7949600 | [F ]
3-8-10-23 | [HS Code ]
29339900 | [Storage Class]
12 - Non Combustible Liquids |
| Hazard Information | Back Directory | [Description]
Propidium iodide (PI) is membrane impermeant and generally excluded from viable cells. However, it can easily penetrate dead or damaged cells and as such is commonly used for identifying cell viability in a population or as a counterstain in multicolor fluorescent techniques.1 It binds to DNA and RNA by intercalating between the bases. PI is excited at 488-535 nm with an emission maximum of 617 nm. This probe is suitable for fluorescence microscopy and flow cytometry. | [Chemical Properties]
Dark Red Solid | [Uses]
1 mg/mL in water | [Uses]
Antibacterial;Detergent | [Uses]
Propidium Iodide is a phenanthridine compound, a class of compounds with reported activity against several species of trypanosomes. Propidium iodide may be used in flow cytometry to evaluate cell viab
ility when used with other dyes that stain viable cells or cells that are early in the apoptosis process. | [Uses]
Propidium iodide is the most common red-fluorescent nuclear stain. It can also be excited using excitation filters appropriate for green-fluorescent dyes. | [Uses]
Used as fluorescent stain for nucleic acids,and used in flow cytometry to evaluate cell viability | [Definition]
ChEBI: Propidium iodide is an organic iodide salt. It contains a propidium. | [General Description]
Extinction coefficient(493 nm): 5900 M -1cm-1;(287 nm): 55,700 M -1cm-1; | [Biochem/physiol Actions]
Primary TargetMembrane impermeable DNA intercalator | [storage]
+4°C | [Purification Methods]
It crystallises as red crystals from H2O containing a little KI. It fluoresces strongly with nucleic acids. [Watkins J Chem Soc 3064 1952, Beilstein 22 III/IV 5519.] TOXIC. | [References]
[1] SIMON JOHNSON David C Vy Nguyen. Assessment of Cell Viability[J]. Current Protocols in Cytometry, 2013, 64 1. DOI: 10.1002/0471142956.cy0902s64 | [Abs/Em Maxima]
537 (complex)/616 (complex) nm |
|
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