| Chemical Properties | Back Directory | [form ]
Oil | [color ]
White to off-white | [InChIKey]
UZZSJVSWGGAHCH-UHFFFAOYSA-N | [SMILES]
C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC |
| Hazard Information | Back Directory | [Uses]
m-PEG24-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG24-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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Xinyanpomei
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15850660754 |
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http://www.xinyanpomei.com |
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