| Identification | Back Directory | [Name]
MPEG8-N3 | [CAS]
869718-80-9 | [Synonyms]
MPEG8-N3
azido-mPEG8
m-PEG8-Azide
Methyl-PEG8-Azide
O-(2-Azidoethyl)-O'-methylheptaethylene Glycol
25-Azido-2,5,8,11,14,17,20,23-octaoxapentacosane > | [Molecular Formula]
C17H35N3O8 | [MDL Number]
MFCD13184962 | [MOL File]
869718-80-9.mol | [Molecular Weight]
409.475 |
| Chemical Properties | Back Directory | [refractive index ]
1.4590 to 1.4630 | [storage temp. ]
Store at Room Tem. | [form ]
clear liquid | [color ]
Colorless to Light yellow to Light orange |
| Hazard Information | Back Directory | [Description]
m-PEG8-azide is a monodisperse PEG linker containing an azide group. It isreactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. | [Uses]
m-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74 |
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