| Identification | More | [Name]
2-Chloro-5-nitrobenzoyl chloride | [CAS]
25784-91-2 | [Synonyms]
2-CHLORO-5-NITROBENZOYL CHLORIDE
2-chloro-5-nitro-benzoylchlorid
Benzoyl chloride, 2-chloro-5-nitro-
2-Chloro-5-Nitrobenzoyl
2-Chloro-5-nitrobenzoic acid chloride | [EINECS(EC#)]
247-262-4 | [Molecular Formula]
C7H3Cl2NO3 | [MDL Number]
MFCD00059180 | [Molecular Weight]
220.01 | [MOL File]
25784-91-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
3261 | [TSCA ]
T | [HS Code ]
2916.39.7900 | [HazardClass ]
8 | [PackingGroup ]
II |
| Hazard Information | Back Directory | [Biological Activity]
2-Chloro-5-nitrobenzoyl chloride (2CNBCl) is an amide that contains a terminal alkyne. It is synthesized from the corresponding thionyl chloride and ethanolamine in the presence of carbon tetrachloride. 2CNBCl has been shown to inhibit the growth of various cancer cell lines, including those derived from melanoma, lung, breast, and colon cancer cells. 2CNBCl also inhibits the production of growth factor proteins such as platelet-derived growth factor (PDGF). 2CNBCl has also been shown to inhibit DNA synthesis by interacting with enzymes involved in the process. |
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