| Identification | More | [Name]
3-Methylbenzoyl chloride | [CAS]
1711-06-4 | [Synonyms]
3-METHYLBENZOYL CHLORIDE
M-METHYLBENZOYL CHLORIDE
M-TOLUOYL CHLORIDE
M-TOLUYL CHLORIDE
3-methyl-benzoylchlorid
3-Toluoyl chloride
3-toluoylchloride
meta Methyl benzoyl chloride
Toluoyl chloride
toluoylchloride
meta-toluoyl chloride
3-ToluylChloride
Benzoyl chloride, 3-methyl-(9CI)
m-Toluoyl chloride(m-Toluicchloride)
3-METHYLBENZOYL CHLORIDE/M-TOLUOYL CHLORIDE
3-Methylbenzenecarbonyl chloride
3-Methylbenzoic acid chloride
m-Methylbenzoic acid chloride | [EINECS(EC#)]
216-976-8 | [Molecular Formula]
C8H7ClO | [MDL Number]
MFCD00000681 | [Molecular Weight]
154.59 | [MOL File]
1711-06-4.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to light brown liquid | [Melting point ]
-23°C | [Boiling point ]
86 °C/5 mmHg (lit.) | [density ]
1.17
| [refractive index ]
1.5475-1.5495
| [Fp ]
76 °C
| [storage temp. ]
Inert atmosphere,2-8°C | [form ]
Liquid | [color ]
Clear colorless to light brown | [Specific Gravity]
1.17 | [Water Solubility ]
Reacts with water. | [Sensitive ]
Moisture Sensitive | [BRN ]
878419 | [InChI]
1S/C8H7ClO/c1-6-3-2-4-7(5-6)8(9)10/h2-5H,1H3 | [InChIKey]
YHOYYHYBFSYOSQ-UHFFFAOYSA-N | [SMILES]
Cc1cccc(c1)C(Cl)=O | [CAS DataBase Reference]
1711-06-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzoyl chloride, 3-methyl-(1711-06-4) | [EPA Substance Registry System]
1711-06-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R36/37:Irritating to eyes and respiratory system . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) . | [RIDADR ]
3265 | [WGK Germany ]
1 | [RTECS ]
DM6644000 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29163990 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to light brown liquid | [Uses]
m-Toluoyl chloride has been used to derivatize the C1-C4 aliphatic amines for their determination in air by HPLC. It has been used in determination of atmospheric ammonia by denuder-sampling and HPLC-UV detection. | [General Description]
m-Toluoyl chloride is an efficient derivatization reagent for amines. | [Synthesis]
In a 1000 mL three-necked flask equipped with a thermometer, a mechanical stirrer, a reflux condenser tube and an off-gas absorption device, 540.56 g of m-methylbenzoic acid, 573.0 g of thionyl chloride and 1.0 g of N,N-dimethylformamide were added sequentially. The reaction mixture was heated to 90°C and the reaction was continuously stirred at this temperature for 3 hours. Upon completion of the reaction, the system was clear. The excess thionyl chloride was removed by distillation under reduced pressure, and 610.0 g of m-toluoyl chloride was finally obtained, which was determined to have a purity of 98.2% and a yield of 99.3%. | [References]
[1] Patent: CN107417518, 2017, A. Location in patent: Paragraph 0028
[2] Patent: CN105348085, 2016, A. Location in patent: Paragraph 0026; 0027; 0028; 0029; 0030
[3] Patent: CN107400052, 2017, A. Location in patent: Paragraph 0016
[4] Canadian Journal of Chemistry, 1963, vol. 41, p. 2962 - 2968
[5] Chemische Berichte, 1879, vol. 12, p. 2300 |
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