257879-35-9

Directory

257879-35-9 Structure

Identification	Back Directory
[Name] PKCβ Inhibitor
[CAS] 257879-35-9
[Synonyms] KUN79359 PKCβ Inhibitor PKCβ inhibitor 1 3-anilino-4-[1-(3-imidazol-1-ylpropyl)indol-3-yl]pyrrole-2,5-dione 1H-Pyrrole-2,5-dione, 3-[1-[3-(1H-imidazol-1-yl)propyl]-1H-indol-3-yl]-4-(phenylamino)-
[Molecular Formula] C24H21N5O2
[MDL Number] MFCD22124896
[MOL File] 257879-35-9.mol
[Molecular Weight] 411.46

Chemical Properties	Back Directory
[solubility ] DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 0.25 mg/ml
[form ] A solid
[color ] Yellow to orange

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H302-H315-H319-H335
[Precautionary statements ] P261-P305+P351+P338

Hazard Information	Back Directory
[Uses] 3-Anilino-4-[1-(3-imidazol-1-ylpropyl)indol-3-yl]pyrrole-2,5-dion is an anilino-monoindolylmaleimide compound that acts as a potent and selective PKCβ inhibitor.3-Anilino-4-[1-(3-imidazol-1-ylpropyl)indol-3-yl]pyrrole-2,5-dione is a selective JAK3 inhibitor with selectivity over JAK2 and TYK2 for potential treatment of rheumatoid arthritis.
[Definition] ChEBI: 3-anilino-4-[1-[3-(1-imidazolyl)propyl]-3-indolyl]pyrrole-2,5-dione is a member of maleimides.
[IC 50] human PKCβ1: 21 nM (IC₅₀); human PKCβ2: 5 nM (IC₅₀); PKCα: 331 nM (IC₅₀)

257879-35-9 suppliers list

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Website:	www.atkchemical.com

Company Name:	Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel:	028-81700200 18116577057
Website:	https://www.weikeqi-biotech.com/

Company Name:	Shanghai Beckham Medical Technology Co., Ltd
Tel:	021-13816613772 13816613772
Website:	https://www.chemicalbook.com/ShowSupplierProductsList16976/0.htm

Company Name:	Shanghai EFE Biological Technology Co., Ltd.
Tel:	021-65675885 18964387627
Website:	http://www.efebio.com

Company Name:	Shanghai YuanYe Biotechnology Co., Ltd.
Tel:	021-61312847; 18021002903
Website:	http://www.shyuanye.com

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840 18892239720
Website:	http://www.jm-bio.com/

Company Name:	Aikon International Limited
Tel:	025-66113011 13155353615
Website:	http://www.aikonchem.com

Company Name:	ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel:	18818260767
Website:	http://www.chemegen.com

Company Name:	Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel:	021-58461859 15821823057
Website:	http://www.aivichem.com

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840 15801484223;
Website:	http://www.jm-bio.com/

Company Name:	Shanghai Huici Pharmaceutical Technology Co., LTD
Tel:	133-31922809 19372841038
Website:	www.pharmahuici.com

Tags:257879-35-9 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login