| Identification | Back Directory | [Name]
S-(2,4-Dinitrophenyl)-Glutathione | [CAS]
26289-39-4 | [Synonyms]
Dinitrophenylglutathione
2,4-Dinitrophenyl-S-glutathione
γGlu-S-(2,4-Dinitrophenyl)-L-Cys-Gly-OH
L-γGlu-S-(2,4-Dinitrophenyl)-L-Cys-Gly-OH
N-[L-γ-Glutamyl-S-(2,4-dinitrophenyl)-L-cysteinyl]glycine | [Molecular Formula]
C16H19N5O10S | [MOL File]
26289-39-4.mol | [Molecular Weight]
473.41 |
| Chemical Properties | Back Directory | [Appearance]
Light Yellow Solid | [Melting point ]
210-212° dec. | [Boiling point ]
895.1±65.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Water: Slightly Soluble | [form ]
A solid | [pka]
2.21±0.10(Predicted) |
| Hazard Information | Back Directory | [Chemical Properties]
Light Yellow Solid | [Uses]
A substrate for Glutathione-S-Transferase, with a kinetically determined dissociation constant of 7uM | [Definition]
ChEBI: A Glu-Cys-Gly tripeptide glutathione conjugate containing a 2,4-dinitrophenyl substituent on the S of Cys. | [Description]
S-(2,4-Dinitrophenyl)-glutathione is a substrate for glutathione-S-transferase with a kinetic dissociation constant of 7 μM. In vitro, it is transported by multidrug resistance protein 1 (MDR1) and MDR3, which are transporters that confer resistance to some chemotherapeutics. | [References]
[1] V L SCHRAMM. Kinetic studies and active site-binding properties of glutathione S-transferase using spin-labeled glutathione, a product analogue.[J]. The Journal of Biological Chemistry, 1984, 259 2: 714-722.
[2] H ZENG. Transport of amphipathic anions by human multidrug resistance protein 3.[J]. Cancer research, 2000, 60 17: 4779-4784.
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Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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