264609-13-4

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264609-13-4 Structure

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[Uses] Edonentan (BMS-207940), a selective antagonist of the endothelin A (ETA) receptor, has been proposed for the treatment of congestive heart failure.
[in vivo] Edonentan (3-10 μmol/kg, orally) blocks big ET-1 pressor responses^[1]. Edonentan (BMS 207940) shows improved systemic clearance (Cl) and steady-state volume of distribution (Vss) in comparison to BMS-193884 (HY-19263)^[1].
[IC 50] ET_A: 10 pM (Ki)

264609-13-4 suppliers list

Company Name:	Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel:	021-33632979
Website:	www.tsbiochem.com

Company Name:	Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel:	+86-400-002-6226 +86-13028896684;
Website:	https://www.rrkchem.com

Company Name:	Jinan ponder chemical co. LTD
Tel:	0531-0000
Website:	www.chemicalbook.com/ShowSupplierProductsList546697/0_EN.htm

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