| Identification | More | [Name]
3-CHLORO-2-PYRAZINE-CARBOXYLIC ACID | [CAS]
27398-39-6 | [Synonyms]
3-CHLORO-2-PYRAZINE-CARBOXYLIC ACID
3-CHLORO-PYRAZINE-2-CARBOXYLIC ACID
RARECHEM AL BO 0855 | [Molecular Formula]
C5H3ClN2O2 | [MDL Number]
MFCD01318438 | [Molecular Weight]
158.54 | [MOL File]
27398-39-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
116-117 °C (decomp) | [Boiling point ]
317.0±37.0 °C(Predicted) | [density ]
1.579±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [pka]
1.51±0.25(Predicted) | [Appearance]
Off-white to light brown Solid | [InChI]
InChI=1S/C5H3ClN2O2/c6-4-3(5(9)10)7-1-2-8-4/h1-2H,(H,9,10) | [InChIKey]
PMRPVXLESNMKLG-UHFFFAOYSA-N | [SMILES]
C1(C(O)=O)=NC=CN=C1Cl | [CAS DataBase Reference]
27398-39-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P305+P351+P338 | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [HS Code ]
2933998090 |
| Hazard Information | Back Directory | [Uses]
3-Chloro-2-pyrazinecarboxylic Acid is used in the synthesis of a novel inhibitor (CX-4945) of protein kinase CK2 in the treatment of cancer. Also used in the synthesis of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase. |
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