| Identification | More | [Name]
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID | [CAS]
28166-41-8 | [Synonyms]
2-CYANO-3-(4-HYDROXYPHENYL)ACRYLIC ACID
4-HCCA
ACCA
A-CYANO-4-HYDROXYCINNAMIC ACID
ALPHA-CCA
ALPHA-CHCA
ALPHA-CYANO
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
LABOTEST-BB LT00159295
alpha-cyano-4-hydroxycinnamate
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID, USE
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID PGE.WITH 10 X 25 MG
α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA
2-Cyano-3-(4-hydroxyphenyl)propenoic acid
α-Cyano-4-hydroxybenzenepropenoic acid | [EINECS(EC#)]
248-879-1 | [Molecular Formula]
C10H7NO3 | [MDL Number]
MFCD00004204 | [Molecular Weight]
189.17 | [MOL File]
28166-41-8.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow crystalline powder | [Melting point ]
245-250 °C(lit.)
| [Boiling point ]
324.41°C (rough estimate) | [density ]
1.3175 (rough estimate) | [refractive index ]
1.5400 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
methanol: 10 mg/mL, clear
| [form ]
powder
| [pka]
0.85±0.10(Predicted) | [color ]
yellow
| [Water Solubility ]
H2O: slightly soluble
methanol: water: soluble
polar organic solvents: soluble | [BRN ]
3271427 | [InChI]
InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14) | [InChIKey]
AFVLVVWMAFSXCK-VMPITWQZSA-N | [SMILES]
C(O)(=O)C(C#N)=CC1=CC=C(O)C=C1 | [CAS DataBase Reference]
28166-41-8(CAS DataBase Reference) | [Absorption]
≥2000 at 337nm (mol. absorption) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
10-23 | [HS Code ]
29269090 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow crystalline powder | [Uses]
inhibitor of mitochondrial pyruvate transport | [Definition]
ChEBI: Alpha-cyano-4-hydroxycinnamic acid is a monohydroxycinnamic acid that is 4-hydroxycinnamic acid in which the hydrogen alpha- to the carboxy group is replaced by a cyano group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of peptides and oligonucleotides. It has a role as a MALDI matrix material. It is a nitrile, a member of phenols and a monohydroxycinnamic acid. | [General Description]
α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase. | [Biochem/physiol Actions]
α-Cyano-4-hydroxycinnamic acid acts as a specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport. It is also reported to block β-cell apical anion exchange (IC50 of 2.4 mM). | [storage]
Store at -20°C |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
|