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141942-85-0

141942-85-0 Structure

141942-85-0 Structure
IdentificationMore
[Name]

Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
[CAS]

141942-85-0
[Synonyms]

ATS-5
BUTANOIC ACID, 4-CYANO-3-HYDROXY-, ETHYL ESTER, (R)
BUTANOIC ACID 4-CYANO-3-HYDROXY-ETHYL ESTER, (S)
ETHYL (3R)-4-CYANO-3-HYDROXY-BUTANOATE
ETHYL (R)-4-CYANO-3-HYDROXYBUTANOATE
ETHYL-(R)-(+)-4-CYANO-3-HYDROXYBUTANOATE
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
ETHYL (R)-(-)-4-CYANO-3-HYDROXYBUTYRATE
ETHYL (R)-4-CYANO-3-HYDROXYBUTYRATE
ETHYL (S)-4-CYANO-3-HYDROXYBUTANOATE
ETHYL (S)-(+)-4-CYANO-3-HYDROXYBUTYRATE
ETHYL(S)-4-CYANO-3-HYDROXY-BUTYRATE
(R)-(-)-4-CYANO-3-HYDROXYBUTYRIC ACID ETHYL ESTER
(R)-4-CYANO-3-HYDROXYBUTYRIC ACID ETHYL ESTER
(R)-(-)-ETHYL 4-CYANO-3-HYDROXYBUTYRATE
(R)-ETHYL 4-CYANO-3-HYDROXYBUTYRATE
(S)-4-CYANO-3-HYDROXYBUTANOATE ETHYL
(S)-ETHYL-4-CYANO-3-HYDROXYBUTYRATE
(R)-4-Cyano-3-hydroxy butanoate
(R)-4-cyano-3-hydroxybutyric
[Molecular Formula]

C7H11NO3
[MDL Number]

MFCD00672878
[Molecular Weight]

157.17
[MOL File]

141942-85-0.mol
Chemical PropertiesBack Directory
[Appearance]

yellow liquid
[bp ]

270 °C(lit.)
[alpha ]

-5 º (neat)
[density ]

1.114 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.448(lit.)
[Fp ]

>230 °F
[BRN ]

5328715
[CAS DataBase Reference]

141942-85-0(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

1
[HS Code ]

29269090
Questions And Answer(Q&A)Back Directory
[Application]

Hydroxyglutaryl coenzyme A (HMG-CoA) reductase inhibitors are a new class of lipid-lowering drugs, and they have a market share of more than 10 billion US dollars in the current pharmaceutical field. They can selectively inhibit the rate-limiting enzyme HMG-CoA reductase in cholesterol synthesis in the liver, reduce liver lipoprotein production, and increase the expression of low-density lipoprotein (LDL) cholesterol receptors, thereby reducing plasma cholesterol levels. They can also significantly reduce very low-density lipoprotein (VLDL) and triglycerides, and increase anti-atherosclerotic high-density protein (HDL), preventing atherosclerosis and coronary heart disease.
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate is an important intermediate for the synthesis of HMG-CoA reductase inhibitors. If it is used as a raw material, synthetic atorvastatin is mainly used for the treatment of hypercholesterolemia and mixed hyperlipidemia, coronary heart disease and stroke.
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate, 98%(141942-85-0)
[TCI AMERICA]

Ethyl (R)-(-)-4-Cyano-3-hydroxybutyrate,>97.0%(GC)(141942-85-0)
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