| Identification | Back Directory | [Name]
WD2000-012547 | [CAS]
283172-68-9 | [Synonyms]
WD2000-012547
6H-Pyrrolo[4,3,2-ef][2]benzazepin-6-one, 1,3,4,5-tetrahydro-2-phenyl- | [Molecular Formula]
C17H14N2O | [MDL Number]
MFCD31544394 | [MOL File]
283172-68-9.mol | [Molecular Weight]
262.31 |
| Chemical Properties | Back Directory | [Melting point ]
249-255 °C (decomp) | [Boiling point ]
600.2±44.0 °C(Predicted) | [density ]
1.270±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
14.94±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKi of 8.221. | [IC 50]
PARP-1: 8.221 (pKi) | [References]
[1] Fatima S, et al. Multiple receptor conformation docking, dock pose clustering and 3D QSAR studies on human poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. J Recept Signal Transduct Res. 2014 Oct;34(5):417-30. DOI:10.3109/10799893.2014.917323 |
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