| Identification | Back Directory | [Name]
Cyclosporin A-Derivative 1 Free base | [CAS]
286852-20-8 | [Synonyms]
Cyclosporin A-Derivative 1 Free base
N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl- | [Molecular Formula]
C65H117N11O14 | [MDL Number]
MFCD31814419 | [MOL File]
286852-20-8.mol | [Molecular Weight]
1276.69 |
| Chemical Properties | Back Directory | [Boiling point ]
1225.9±65.0 °C(Predicted) | [density ]
1.093±0.06 g/cm3(Predicted) | [solubility ]
DCM, Methanol | [form ]
Solid | [pka]
13.07±0.46(Predicted) | [color ]
Off-White | [Sequence]
Leu-Val-Leu-Ala-{d-Ala}-Leu-Leu-Val-{Aaa}-{Abu}-{Sar} |
| Hazard Information | Back Directory | [Uses]
N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation. |
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| Company Name: |
Energy Chemical
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| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
TargetMol
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| Telephone: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
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