| Identification | Back Directory | [Name]
2-(3,5-Difluorophenyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline | [CAS]
2890188-81-3 | [Synonyms]
2-(3,5-Difluorophenyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline | [Molecular Formula]
C17H17F2NO2 | [MOL File]
2890188-81-3.mol | [Molecular Weight]
305.32 |
| Chemical Properties | Back Directory | [Boiling point ]
437.336±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.231±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
2.574±0.40(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MAO-B-IN-17 is a selective monoamine oxidase B (MAO-B) inhibitor with the IC50 value of 5.08 μM. MAO-B-IN-17 can be used in Parkinson’s disease research[1]. | [IC 50]
hMAO-B: 5.08 μM (IC50); hMAO-A: >100 μM (IC50) | [References]
[1] Makito Yamada, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. ACS Med. Chem. Lett. 2022. |
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