| Identification | More | [Name]
4-Oxo-2,2,6,6-tetramethylpiperidinooxy | [CAS]
2896-70-0 | [Synonyms]
1-OXYL-2,2,6,6-TETRAMETHYL-4-PIPERIDONE
2,2,6,6-TETRAMETHYL-4-OXO-1-PIPERIDINYLOXY
2,2,6,6-TETRAMETHYL-4-OXOPIPERIDINOOXY
2,2,6,6-TETRAMETHYL-4-PIPERIDONE 1-OXYL
4-OXO-2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY
4-OXO-2,2,6,6-TETRAMETHYL-4-PIPERIDINYLOXY
4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL
4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY
4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY, FREE RADICAL
4-OXO-TEMPO
4-OXO-TEMPO, FREE RADICAL
TEMPONE
TIMTEC-BB SBB008633
1-Piperidinyloxy radical, 2,2,6,6-tetramethyl-4-oxo-
2,2,6,6-tetramethyl-4-oxo-1-piperidinylox
2,2,6,6-tetramethyl-4-oxo-piperidin-1-oxyl
2,2,6,6-tetramethyl-4-oxo-piperidinoox
2,2,6,6-Tetramethyl-4-oxo-piperidinoxy
2,2,6,6-Tetramethyl-4-piperidone 1-nitroxide
2,2,6,6-Tetramethylpiperidone-1-oxyl | [EINECS(EC#)]
220-778-7 | [Molecular Formula]
C9H16NO2 * | [MDL Number]
MFCD00006187 | [Molecular Weight]
170.23 | [MOL File]
2896-70-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Pink Needles | [Melting point ]
33-38 °C
| [Boiling point ]
299.88°C (rough estimate) | [density ]
1.0710 (rough estimate) | [vapor pressure ]
2.254Pa at 25℃ | [refractive index ]
1.4640 (estimate) | [storage temp. ]
0-6°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
Needles, Crystals or Crystalline Powder | [color ]
Orange | [Water Solubility ]
Soluble in water (partly), acetone, DMSO, 100% ethanol, and diethylether. Insoluble in water. | [Usage]
A spin label for ESR studies | [BRN ]
1818579 | [InChI]
1S/C9H16NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h5-6H2,1-4H3 | [InChIKey]
WSGDRFHJFJRSFY-UHFFFAOYSA-N | [SMILES]
CC1(C)CC(=O)CC(C)(C)N1[O] | [LogP]
0.28 at 22℃ | [CAS DataBase Reference]
2896-70-0(CAS DataBase Reference) | [NIST Chemistry Reference]
1-Piperidinyloxy, 2,2,6,6-tetramethyl-4-oxo-(2896-70-0) | [EPA Substance Registry System]
2896-70-0(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS09 | [Signal word ]
Warning | [Hazard statements ]
H400 | [Precautionary statements ]
P273 | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
3
| [RTECS ]
TN9200000
| [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
9 | [HS Code ]
29333990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Acute 1 |
| Hazard Information | Back Directory | [Description]
2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS).1 This conversion, followed by ESR, provides an indirect way to monitor ROS production in biological systems. TEMPONE is the 4-oxo derivative of TEMPO. In addition to possible uses as a spin trap, this nitroxyl radical can be used in hydrogen transfer experiments and as a polarizing agent in dynamic nuclear polarization NMR spectroscopy.2,3 TEMPONE and other nitroxyl radicals have also been shown to reduce mean arterial pressure in spontaneously hypertensive rats when administered intravenously.4 | [Chemical Properties]
Pink Needles | [Uses]
A spin label for ESR studies | [General Description]
4-Oxo-TEMPO is formed by the reaction of 2,2,6,6-tetramethyl-4-piperidone (4-oxo-TMP) and 1O2. It is a stable paramagnetic product formed during the irradiation of TiO2 in aqueous suspensions. | [Flammability and Explosibility]
Nonflammable | [References]
[1] ADAM WU. Nitroxyl Radical Plus Hydroxylamine Pseudo Self-Exchange Reactions: Tunneling in Hydrogen Atom Transfer[J]. Journal of the American Chemical Society, 2009, 131 33: 11985-11997. DOI: 10.1021/ja904400d
[2] LUMATA L, MERRITT M, KHEMTONG C, et al. The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy?[J]. RSC Advances, 2012, 33: 12812-12817. DOI: 10.1039/c2ra21853d
[3] KINJAL PATEL. Acute antihypertensive action of nitroxides in the spontaneously hypertensive rat.[J]. American journal of physiology. Regulatory, integrative and comparative physiology, 2006, 290 1: R37-43. DOI: 10.1152/ajpregu.00469.2005 |
| Well-known Reagent Company Product Information | Back Directory | [Acros Organics]
4-Oxo-2,2,6,6-tetramethylpiperidinooxy, free radical, 95%(2896-70-0) | [Alfa Aesar]
4-Oxo-TEMPO, free radical, 96%(2896-70-0) | [Sigma Aldrich]
2896-70-0(sigmaaldrich) | [TCI AMERICA]
4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical,>95.0%(GC)(T)(2896-70-0) |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Shanghai Ennopharm Co., Ltd.
|
| Telephone: |
+86 (21) 6435-5022 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList13640/0_EN.htm |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
T&W GROUP
|
| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
|