| Chemical Properties | Back Directory | [Boiling point ]
627.0±55.0 °C(predicted) | [density ]
1.367±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
2.97±0.40(predicted) | [color ]
White to off-white (Solid) |
| Hazard Information | Back Directory | [Uses]
JAB-2485 is a potent and selective Aurora kinase A (AURKA) inhibitor, with an IC50 of 0.33 nM. JAB-2485 exhibits around 1700-fold selectivity for AURKA over AURKB. JAB-2485 induces cell cycle arrest and apoptosis. JAB-2485 can be used for the research of cancer[1]. | [References]
[1] Yang G, et, al. Abstract 1645: JAB-2485: A potent, highly selective small-molecule Aurora kinase A inhibitor that targets cell division. Cancer Res (2023) 83 (7_Supplement): 1645. |
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| Company Name: |
Madision Biomedical Co., Ltd.
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| Tel: |
028-87439248 19150327610 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList30539/0_EN.htm |
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