| Identification | More | [Name]
BOC-D-PHG-OH | [CAS]
2900-27-8 | [Synonyms]
BOC-D-ALPHA-PHENYLGLYCINE
BOC-D-A-PHENYLGLYCINE
BOC-D-PHENYLGLYCINE
BOC-D-(PHENYL)GLY-OH
BOC-D-PHG
BOC-D-PHG-OH
N-ALPHA-T-BOC-D-PHENYLGLYCINE
N-ALPHA-T-BUTYLOXYCARBONYL-D-PHENYLGLYCINE
N-ALPHA-TERT-BUTYLOXYCARBONYL-D-PHENYLGLYCINE
N-BOC-D-PHENYLGLYCINE
RARECHEM EM WB 0178
(R)-TERT-BUTOXYCARBONYLAMINO-PHENYL-ACETIC ACID
T-BUTOXYCARBONYL-D-PHENYLGLYCINE
Boc-Phg-OH~N-(tert-Butoxycarbonyl)-L-phenylglycine
N-tert-Butoxycarbonyl-L-phenylglycine
NALPHA-tert-Butoxycarbonyl-D-phenylglycine
BOC-L-PHENYLGLYCINE(BOC-PHG-OH)
N-(tert-Butoxycarbonyl)-L-2-phenylglycine
N-Boc-L-2-phenylglycine
N-(tert-butoxycarbonyl)-L-alpha-phenylglycine | [EINECS(EC#)]
-0 | [Molecular Formula]
C13H17NO4 | [MDL Number]
MFCD00062043 | [Molecular Weight]
251.28 | [MOL File]
2900-27-8.mol |
| Questions And Answer | Back Directory | [Synthesis]
Using L-2-phenylglycine as a starting material, the target compound BOC-D-PHG-OH was prepared by reacting it with di-tert-butyl dicarbonate under Et 3 N/MeOH conditions with Boc protection. The reaction formula for the preparation of BOC-D-PHG-OH is shown in the figure below:  |
| Chemical Properties | Back Directory | [Appearance]
White to off-white crystalline powder | [Melting point ]
88-91 °C
| [Boiling point ]
407.2±38.0 °C(Predicted) | [density ]
1.182±0.06 g/cm3(Predicted) | [refractive index ]
142 ° (C=1, EtOH) | [storage temp. ]
Store at RT. | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [Water Solubility ]
Insoluble in water | [form ]
powder to crystal | [pka]
3.51±0.10(Predicted) | [color ]
White to Almost white | [Optical Rotation]
[α]20/D +144±2°, c = 1% in ethanol | [BRN ]
3592362 | [Major Application]
peptide synthesis | [InChI]
InChI=1/C13H17NO4/c1-13(2,3)18-12(17)14-10(11(15)16)9-7-5-4-6-8-9/h4-8,10H,1-3H3,(H,14,17)(H,15,16)/t10-/s3 | [InChIKey]
HOBFSNNENNQQIU-JQHDBZEONA-N | [SMILES]
[C@H](C1C=CC=CC=1)(C(=O)O)NC(=O)OC(C)(C)C |&1:0,r| | [CAS DataBase Reference]
2900-27-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29242990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white crystalline powder | [Uses]
Boc-L-Phg-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance. | [reaction suitability]
reaction type: Boc solid-phase peptide synthesis |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
|