| Identification | Back Directory | [Name]
Toloxatone | [CAS]
29218-27-7 | [Synonyms]
Humoryl
Perenum
69276MD
MD-69276
Toloxatone
Taloxotone
Delalande 69276
Toloxatone USP/EP/BP
Toloxatone - MD 69276
ToloxatonetoloxatonetoloxatoneToloxatone
5-Hydroxymethyl-3-(m-tolyl)oxazolidin-2-one
5-(Hydroxymethyl)-3-(m-tolyl)oxazolidin-2-one
5-Hydroxymethyl-3-(3-methylphenyl)oxazolidin-2-one
5-(hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone
2-OXAZOLIDINONE, 5-(HYDROXYMETHYL)-3-(3-METHYLPHENYL)-
Toloxatone,Monoamine Oxidase,MD69276,MD-69276,MAO,inhibit,Inhibitor | [EINECS(EC#)]
249-522-2 | [Molecular Formula]
C11H13NO3 | [MDL Number]
MFCD00865391 | [MOL File]
29218-27-7.mol | [Molecular Weight]
207.23 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [RIDADR ]
3249 | [WGK Germany ]
3 | [RTECS ]
RQ2867500 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
LD50 orally in mice (mg/kg): 1850 (Fauran); also reported as 1500 (Raynaud) |
| Hazard Information | Back Directory | [Description]
Toloxatone is a selective, reversible and competitive inhibitor of type A
monoamine oxidase (MAO-A) which shows clinical utility as an antidepressant. It
is reportedly free of the "cheese effect" in man, possibly due to the reversible
nature of its inhibitory effect on intestinal MAO-A in the presence of high
concentrations of tyramine. | [Originator]
Delalande (France) | [Uses]
Toloxatone is a monoamine oxidase-A (MAO-A) inhibitor. | [Definition]
ChEBI: 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one is a member of the class of oxazolidinones that is 5-(hydroxymethyl)-1,3-oxazolidin-2-one substituted by a 3-methylphenyl group at position 3. It is a member of toluenes, an oxazolidinone and a primary alcohol. | [Brand name]
HUMORYL |
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|