| Identification | Back Directory | [Name]
Vidarabine monophosphate | [CAS]
29984-33-6 | [Synonyms]
Ara-A
cl-808
ARA-AMP
VIDARABINE PHOSPHATE
vidarabinemonophosphate
Vidarabine Monophasphate
vidarabine-5’-monophosphate
arabinosyladeninemonophosphate
adeninearabinosidemonophosphate
5’-arabinosyladeninemonophosphate
adeninearabinoside5’-monophosphate
Adenine-9-beta-D-arabinofuranoside-5
9-(5-O-phosphono-β-D-arabinofuranosyl)adenine
ADENINE-BETA-D-ARABINOFURANOSIDE-5'-PHOSPHATE
9-BETA-D-ARABINOFURANOSYLADENINE MONOPHOSPHATE
9-(b-D-Arabinofuranosyl)adenine 5'-monophosphate
9-(5-O-phosphono-beta-D-arabinofuranosyl)adenine
Adenine-9-β-D-arabinofuranoside-5’-monophosphate
adenine 9-beta-arabinofuranoside 5'-monophosphate
9-BETA-D-ARABINOFURANOSYLADENINE-5'-MONOPHOSPHATE
ADENINE-9-BETA-D-ARABINOFURANOSIDE-5'-MONOPHOSPHATE
ADENINE 9-B-D-ARABINOFURANOSIDE5'-MONOPH OSPHATE FR
9-β-D-Arabinofuranosyladenine 5'-(dihydrogen phosphate)
Adenine-9-beta-D-arabinofuranoside-5'-monophosphate,98%
Adenine-9-beta-D-arabinofuranoside-5zzhlxy-monophosphate
9-beta-d-arabinofuranosyl-adenin5’-(dihydrogenphosphate)
9-BETA-D-ARABINOFURANOSYL-ADENINE-5'-MONOPHOSPHORIC ACID
9-(5-o-phosphono-beta-d-arabinofuranosyl)-9h-purin-6-amin
Ara-AMP, 9-β-D-Arabinofuranosyladenine 5μ-monophosphate
9-(beta-d-arabinofuranosyl)adenine5’-(dihydrogenphosphate)
9-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE
Adenine 9-β-D-arabinofuranoside 5′-monophosphate ammonium salt
(2R,3S,4S,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
ADENINE 9-β-D-ARABINOFURANOSIDE 5''-MONOPHOSPHATE (9-β-D-ARABINOFURANOSYLADENINE 5''-MONOPHOSPHATE: ARA-AMP) | [EINECS(EC#)]
249-990-8 | [Molecular Formula]
C10H14N5O7P | [MDL Number]
MFCD00069723 | [MOL File]
29984-33-6.mol | [Molecular Weight]
347.22 |
| Chemical Properties | Back Directory | [Appearance]
Crystalline | [Melting point ]
213 °C
| [Boiling point ]
798.5±70.0 °C(Predicted) | [density ]
2.32±0.1 g/cm3(Predicted) | [storage temp. ]
Store at 0°C | [form ]
Powder | [pka]
1.86±0.10(Predicted) | [color ]
White to Off-white | [Water Solubility ]
Soluble in water at 4mg/ml | [InChI]
InChI=1/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7+,10-/s3 | [InChIKey]
UDMBCSSLTHHNCD-GCTRTDOSNA-N | [SMILES]
O[C@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O |&1:1,2,3,11,r| |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline | [Description]
Vidarabine monophosphate, chemical name:
9-(5-O-Phosphono-beta-D-arabinofuranosyl)adenine is an anti
deoxyribonucleic acid virus drug. IVidarabine triphosphate directly
inhibits DNA polymerase and also acts as a chain terminator in DNA
replication. An adenosine monophosphate analog in which ribose is
replaced by an arabinose moiety. It is the monophosphate ester of
VIDARABINE with antiviral and possibly antineoplastic properties. | [Uses]
Antiviral. | [Application]
Vidarabine monophosphate has broad-spectrum anti-virus effect and can inhibit a variety of DNA
viruses. It is mainly used to treat chronic hepatitis B and other viral
infections, such as herpes zoster, herpes simplex and genital herpes.
It has quick effect and clear curative effect. It is a common drug for
clinical anti-virus treatment. | [Safety Profile]
Moderately toxic byintraperitoneal route. When heated to decomposition itemits very toxic fumes of POx and NOx. |
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