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301222-66-2

301222-66-2 Structure

301222-66-2 Structure
IdentificationMore
[Name]

2-AMINO-5-FLUORO-4-PICOLINE
[CAS]

301222-66-2
[Synonyms]

2-AMINO-4-METHYL-5-FLUOROPYRIDINE
2-AMINO-5-FLUORO-4-PICOLINE
2-Pyridinamine,5-fluoro-4-methyl-(9CI)
2-AMINO-5-FLUORO-4-METHYLPYRIDINE
5-fluoro-4-methylpyridin-2-amine
[Molecular Formula]

C6H7FN2
[MDL Number]

MFCD06659479
[Molecular Weight]

126.13
[MOL File]

301222-66-2.mol
Questions And AnswerBack Directory
[Preparation]

The target compound was prepared by ammonolysis of 2-chloro-4-methyl-5-fluoropyridine as the starting material; or by Hoffmann degradation of 4-methyl-5-fluoropyridine carboxylic acid as the starting material via acyl chloride and amide intermediates.
[Uses]

Halogenated aminopyridines are a class of structural units with significant applications, widely found in fragrances, pesticides, coal tar, essential oils, and dyes. 4-Methyl-2-amino-5-fluoropyridine, as an important pharmaceutical intermediate and fine chemical raw material, has a wide range of applications and a promising market prospect.
Chemical PropertiesBack Directory
[Melting point ]

145.0 to 149.0 °C
[Boiling point ]

219.3±35.0 °C(Predicted)
[density ]

1.196±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[pka]

5.24±0.24(Predicted)
[CAS DataBase Reference]

301222-66-2(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H312-H315-H319-H332-H335
[Precautionary statements ]

P261-P280-P304+P340-P305+P351+P338-P405-P501a
[Hazard Codes ]

Xi
[Risk Statements ]

22-37/38-41
[Safety Statements ]

26-39
[HazardClass ]

IRRITANT
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sulfuric acid-->Nitric acid-->Sodium nitrite-->Acetic anhydride-->Palladium-->Fluoroboric acid-->4-Methylpyridin-2-amine
Spectrum DetailBack Directory
[Spectrum Detail]

2-AMINO-5-FLUORO-4-PICOLINE(301222-66-2)1HNMR
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