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QP5020 (compound 28) is an inhibitor of QPCTL with an IC50 value of 15 nM. QP5020 has antitumor efficacy[1]. | [References]
[1] Lei Yu, et al. Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy. Signal Transduct Target Ther. 2023, 8, 1. DOI:10.1038/s41392-023-01715-x |
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