ChemicalBook--->CAS DataBase List--->303-43-5

303-43-5

303-43-5 Structure

303-43-5 Structure
IdentificationMore
[Name]

Cholesteryl oleate
[CAS]

303-43-5
[Synonyms]

3beta-hydroxy-5-cholestene 3-oleate
3BETA-HYDROXY-5-CHOLESTENE 3-OLEATE, OLEOYLCHOLESTEROL
5-CHOLESTEN-3BETA-OL 3-(9-OCTADECENOATE)
5-CHOLESTEN-3BETA-OL 3-OLEATE
5-CHOLESTEN-3-BETA-OL OLEATE
CHOLESTEROL OLEATE
CHOLESTERYL CIS-9-OCTADECENOATE
CHOLESTERYL OCTADECENOATE
CHOLESTERYL OLEATE
oleic acid cholesteryl ester
(Z)-(3β)-cholest-5-en-3-yl9-octadecenoate
(Z)-3β-9-octdecenoylcholest-5-ene
9-octadecenoate,(Z)-Cholest-5-en-3-ol(3.beta.)-
9-octadecenoate,(z)-cholest-5-en-3-ol(3beta)
Cholest-5-en-3-ol (3beta)-, 9-octadecenoate, (Z)-
Cholest-5-en-3-yl (9Z)-9-octadecenoate
Cholesteroyl-oleate
cholestreyloleate
Oleoylcholesterol
3β-Hydroxy-5-cholestene 3-oleate
[EINECS(EC#)]

206-142-1
[Molecular Formula]

C45H78O2
[MDL Number]

MFCD00003645
[Molecular Weight]

651.1
[MOL File]

303-43-5.mol
Chemical PropertiesBack Directory
[Appearance]

white to off-white powder, lumpy powder or pale
[Melting point ]

44-47 °C (lit.)
[Boiling point ]

617.95°C (rough estimate)
[density ]

0.9287 (rough estimate)
[refractive index ]

-20 ° (C=2, THF)
[Fp ]

>230 °F
[storage temp. ]

−20°C
[solubility ]

chloroform: 0.1 g/mL, clear, colorless
[form ]

Solid
[color ]

White to Off-White
[BRN ]

2343071
[LogP]

18.284 (est)
[CAS DataBase Reference]

303-43-5(CAS DataBase Reference)
[NIST Chemistry Reference]

Cholesteryl oleate(303-43-5)
[EPA Substance Registry System]

303-43-5(EPA Substance)
Safety DataBack Directory
[WGK Germany ]

3
[TSCA ]

Yes
[HazardClass ]

IRRITANT
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Oleic acid cholesteryl ester(303-43-5).msds
Hazard InformationBack Directory
[Description]

Cholesteryl oleate is a cholesterol ester. It has been used in the generation of nanoparticles and liposomes for drug delivery.
[Chemical Properties]

white to off-white powder, lumpy powder or pale
[Uses]

Cholesteryl oleate was used to study the ability of silicone hydrogel contact lenses to absorb tear lipids, cholesterol and cholesterol esters. It was also used in the development of amperometric cholesterol biosensors.
[Definition]

ChEBI: The (Z)-stereoisomer of cholesteryl octadec-9-enoate.
[Biochem/physiol Actions]

Cholesterol in plasma is present in an esterified form such as Cholesteryl oleate. The liver is a primary source of cholesteryl oleate that enriches the LDL particles when released into plasma. The secretion of lipoproteins enriched with cholesteryl oleate has close correlation with the pathogenesis of coronary artery atherosclerosis.
[storage]

Store at -20°C
[Purification Methods]

Purify the oleate ester by chromatography on silica gel and eluting with MeOH. [Beilstein 6 III 2642.]
Spectrum DetailBack Directory
[Spectrum Detail]

Cholesteryl oleate(303-43-5)MS
Cholesteryl oleate(303-43-5)1HNMR
Cholesteryl oleate(303-43-5)13CNMR
Cholesteryl oleate(303-43-5)IR1
Cholesteryl oleate(303-43-5)IR2
Cholesteryl oleate(303-43-5)IR3
Cholesteryl oleate(303-43-5)Raman
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Cholesteryl oleate, 97%(303-43-5)
[Sigma Aldrich]

303-43-5(sigmaaldrich)
[TCI AMERICA]

Cholesterol Oleate,>85.0%(GC)(303-43-5)
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