| Identification | More | [Name]
3-Bromo-5-chlorobenzonitrile | [CAS]
304854-55-5 | [Synonyms]
3-BROMO-5-CHLOROBENZONITRILE | [Molecular Formula]
C7H3BrClN | [MDL Number]
MFCD06200840 | [Molecular Weight]
216.46 | [MOL File]
304854-55-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
70.7-71.1°C | [Boiling point ]
144 °C / 12mmHg | [density ]
1.74±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [color ]
White to Almost white | [InChI]
InChI=1S/C7H3BrClN/c8-6-1-5(4-10)2-7(9)3-6/h1-3H | [InChIKey]
DRKWKPSNVQVDKZ-UHFFFAOYSA-N | [SMILES]
C(#N)C1=CC(Cl)=CC(Br)=C1 | [CAS DataBase Reference]
304854-55-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
3439 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [PackingGroup ]
III | [HS Code ]
2926907090 |
| Hazard Information | Back Directory | [Uses]
3-Bromo-5-chlorobenzonitrile is the intermediate that is used for the new type anticancer medicine, belongs to the fine-chemical intermediate technical field. | [Synthesis]
A solution of 1,3-dibromo-5-chlorobenzene (10 g, 37.34 mmol), pyridine (6.03 mL) and copper(I) cyanide (3.34 g, 37.34 ) in DMF (57.74 mL) was refluxed under nitrogen for 2 days.
mmol) in DMF (57.74 mL) was refluxed under nitrogen for 2 days. The reaction |
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