| Identification | More | [Name]
1,1-Dichloro-2,2,2-trifluoroethane | [CAS]
306-83-2 | [Synonyms]
1,1,1-TRIFLUORODICHLOROETHANE
1,1-DICHLORO-2,2,2-TRIFLUOROETHANE
2,2-DICHLORO-1,1,1 TRIFLUORETHANE
2,2-DICHLORO-1,1,1-TRIFLUOROETHANE
FC-123
FLON-123
HALOCARBON 123
HCFC-123
1,1,1-Trifluoro-2,2-dichloroethane
2,2-Dichlor-1,1,1-trifluorethan
2,2-Dichlor-1,1,-trifluorethan
2,2-dichloro-1,1,1-trifluoro-ethan
2,2-dichloro-1,1,1-trifluoroethane(hcfc-123)
CF3CHCl2
CFC123
cfc-123
chlorofluorocarbon123
dichloro(trifluoromethyl)methane
dichloro-1,1,1-trifluoroethane
Dichlorotrifluoromethylmethane | [EINECS(EC#)]
206-190-3 | [Molecular Formula]
C2HCl2F3 | [MDL Number]
MFCD00042132 | [Molecular Weight]
152.93 | [MOL File]
306-83-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R39:Danger of very serious irreversible effects.
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
3163 | [WGK Germany ]
1 | [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT, GAS, OZONE DEPLETER | [Safety Profile]
Suspected carcinogen.
Moderately toxic by inhalation. When
heated to decomposition it emits very toxic
fumes of Fand Cl-. See also CHLORINATED
HYDROCARBONS,
ALIPHATIC; and FLUORIDES. | [Hazardous Substances Data]
306-83-2(Hazardous Substances Data) | [Toxicity]
LD50 skin in rabbit: > 2gm/kg |
| Hazard Information | Back Directory | [General Description]
Colorless nonflammable gas. Nearly odorless. | [Reactivity Profile]
2,2-DICHLORO-1,1,1-TRIFLUOROETHANE is chemically inert in many situations, but can react violently with strong reducing agents such as the very active metals and the active metals. They suffer oxidation with strong oxidizing agents and under extremes of temperature. | [Chemical Properties]
1,1-Dichloro-2,2,2-trifluoroethane has a light ethereal odor
with poor warning properties. | [Uses]
HCFC 123 is an interim replacement for the CFCs and is
scheduled for a production phase-out during the 2020s.
Its main application is as a substitute for CFC 11 in centrifugal
chillers used for air conditioning of large buildings. It is
also used in smaller air-conditioning units, and may have
applications in foam blowing, and firefighting and as a
chemical intermediate. | [Health Hazard]
HCFC-123 (2,2-dichloro-1,1,1-trifluoroethane) has evidenced significant human liver toxicity. A group of 17 workers suffered liver damage in a 1997 outbreak. They were involved in containerizing this liquid. HCFC-123 is chemically similar to halothane and has the same toxic metabolite. HCFC- 123 exposure also was implicated as the cause of liver disease in nine industrial workers who had repeated exposure because of a leaking airconditioning system in 1996; the refrigerant also contained HCFC-124. HCFC-124 and HCFC-125 are also structurally similar to halothane. | [Flammability and Explosibility]
Nonflammable | [Carcinogenicity]
An inhalation toxicity/oncogenicity
study was conducted with groups of 80 male and
80 female rats. This study was described earlier in this
section. In addition to the effects on serum chemistry parameters
and the retina, increases in benign tumors of the
pancreas, testes, and liver were reported. As noted above, the survival in
the HCFC 123–exposed animals was better than in the airexposed
controls. These tumors tended to appear near the end of the study and generally were not considered to be the cause
of death. |
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