| Identification | Back Directory | [Name]
4H-1-Benzopyran-4-one, 5-hydroxy-2- (3-hydroxy-4-methoxyphenyl)-7-meth oxy- | [CAS]
32174-62-2 | [Synonyms]
Pilloin
NSC 195196
Persicogein
Luteolin 7,4'-dimethyl ether
Luteolin 4',7-dimethyl ether
Rutoside Trihydrate Impurity 11
5,3'-Dihydroxy-7,4'-dimethoxyflavone
5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxychromen-4-one
2-(3-Hydroxy-4-methoxyphenyl)-7-methoxy-5-hydroxy-4H-1-benzopyran-4-one
5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5-hydroxy-2- (3-hydroxy-4-methoxyphenyl)-7-meth oxy- | [Molecular Formula]
C17H14O6 | [MDL Number]
MFCD28100687 | [MOL File]
32174-62-2.mol | [Molecular Weight]
314.29 |
| Chemical Properties | Back Directory | [Melting point ]
230-232℃ (Decomposition) (methanol ) | [Boiling point ]
569.6±50.0 °C(Predicted) | [density ]
1.402±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
6.33±0.40(Predicted) | [color ]
White to off-white | [InChI]
InChI=1S/C17H14O6/c1-21-10-6-12(19)17-13(20)8-15(23-16(17)7-10)9-3-4-14(22-2)11(18)5-9/h3-8,18-19H,1-2H3 | [InChIKey]
UDBHJDTXPDRDNS-UHFFFAOYSA-N | [SMILES]
C1(C2=CC=C(OC)C(O)=C2)OC2=CC(OC)=CC(O)=C2C(=O)C=1 |
| Hazard Information | Back Directory | [Uses]
Pilloin, a flavonoid isolated from Marrubium cylleneum, exerts a cytotoxic action targeted at the transformed lymphoblasts. Pilloin also possesses anti-inflammatory activity[1]. | [Definition]
ChEBI: Luteolin 4',7-dimethyl ether is a 3'-hydroxyflavonoid, a dimethoxyflavone and a dihydroxyflavone. | [References]
[1] Fotios Michelis, et al. Effects of the Flavonoid Pilloin Isolated from Marrubium cylleneum on Mitogen-Induced Lymphocyte Transformation. Journal Pharmaceutical Biology. 2002.
[2] Yun-Chen Tsai, et al. Pilloin, A Flavonoid Isolated From Aquilaria sinensis, Exhibits Anti-Inflammatory Activity In Vitro and In Vivo. Molecules. 2018 Dec 2;23(12):3177. DOI:10.3390/molecules23123177 |
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