| Identification | Back Directory | [Name]
Benzenamine, 4-[(bromodichloromethyl)sulfonyl]-N-cyclohexyl-2-nitro- | [CAS]
324022-39-1 | [Synonyms]
WNK1-IN-1
Benzenamine, 4-[(bromodichloromethyl)sulfonyl]-N-cyclohexyl-2-nitro- | [Molecular Formula]
C13H15BrCl2N2O4S | [MOL File]
324022-39-1.mol | [Molecular Weight]
446.14 |
| Chemical Properties | Back Directory | [Melting point ]
192-194 °C(Solv: isopropanol (67-63-0)) | [Boiling point ]
531.0±50.0 °C(Predicted) | [density ]
1.709±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
-4.21±0.20(Predicted) | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Uses]
WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer[1]. | [References]
[1] Rodriguez M, et al. Synthesis and Structural Characterization of Novel Trihalo-sulfone Inhibitors of WNK1. ACS Med Chem Lett. 2022 Sep 23;13(10):1678-1684. DOI:10.1021/acsmedchemlett.2c00216 |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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